Researchers have found that a drug which could treat stroke may also prevent Alzheimer's disease.The University of Southern California findings have been published in the Journal of Experimental Medicine.The study shows that the genetically engineered protein 3K3A-APC protects the brains of mice with Alzheimer's-like symptoms, reducing the buildup of toxic peptides and preventing memory loss.3K3A-APC is a genetically modified version of a human blood protein called activated protein C, which reduces inflammation and protects both neurons and the cells that line the walls of blood vessels from death and degeneration. 3K3A-APC has beneficial effects in various mouse models of disease, including traumatic brain injury and multiple sclerosis. It is currently being developed to treat stroke in humans, where it has been shown to be safe, well tolerated, and capable of reducing intracerebral bleeding."Because of its neuroprotective, vasculoprotective, and anti-inflammatory activities in ...
