DELRAY BEACH, Fla. — Second-seeded John Isner advanced to the third round of the Delray Beach Open on Wednesday night, beating Lukas Lacko of Slovakia 6-4, 6-3. The 6-foot-10 American set up a match against eighth-seeded Adrian Mannarino of France, a 6-2, 7-6 (3) winner over Denis Istomin of Uzbekistan in the outdoor hardcourt event