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2018

Новости за 09.10.2018

Using a phiC31 “Disintegrase” to make new attP sites in the Drosophila genome at locations showing chromosomal position effects

Plos.org 

by Mukesh Maharjan, Robert K. Maeda, François Karch, Craig M. Hart

An engineered phiC31 “Disintegrase” able to make an attP site in Drosophila out of an attR-attL pair is described. This was used to generate attP sites at genomic locations where a mini-white (mini-w) transgene was subject to chromosomal position effects (CPE). The first step was random genomic integration of a P-element-based transposon with an insulated mini-w transgene. We then removed the upstream insulator using FLP recombinase to detect CPE. Читать дальше...



The effect of assortative mixing on stability of low helminth transmission levels and on the impact of mass drug administration: Model explorations for onchocerciasis

Plos.org 

by Anneke S. de Vos, Wilma A. Stolk, Sake J. de Vlas, Luc E. Coffeng

Background

Stable low pre-control prevalences of helminth infection are not uncommon in field settings, yet it is poorly understood how such low levels can be sustained, thereby challenging efforts to model them. Disentangling possible facilitating mechanisms is important, since these may differently affect intervention impact. Here we explore the role of assortative (i.e. non-homogenous) mixing and exposure heterogeneity in helminth transmission... Читать дальше...

Interactive reservoir computing for chunking information streams

Plos.org 

by Toshitake Asabuki, Naoki Hiratani, Tomoki Fukai

Chunking is the process by which frequently repeated segments of temporal inputs are concatenated into single units that are easy to process. Such a process is fundamental to time-series analysis in biological and artificial information processing systems. The brain efficiently acquires chunks from various information streams in an unsupervised manner; however, the underlying mechanisms of this process remain elusive. A widely-adopted statistical... Читать дальше...

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Москва

«Искуситель», «Актриса» и «Пиковая дама»: топ 3 спектаклей сентября


The Man In The High Castle crosses the border

Avclub.com 

Inevitably, if a series lasts long enough, the narrative problem of servicing all the characters arises. The actors are under contract, they’re getting paid, so the creative team either has to kill them off or keep them busy somehow. Some of those choices will end up being considerably less compelling than others.…

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J. Crew Columbus Day Sale Offers 40% Off On Fall Basics

Forbes.com 

Today is Columbus Day and many retailers are offering some jaw-dropping sale prices on stylish items. For instance, J.Crew is celebrating Columbus Day by offering customers a chance to receive 40% off their purchase of select women’s apparel, shoes, and accessories.


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Вероника Кудерметова

Кудерметова завоевала свой первый титул Уимблдона в парном разряде.






Из трёх музеев Томской области томичи отправили по почте 500 «тёплых открыток»

В Подмосковье за один вечер молнии три раза ударили в дома

Жители Прикамья активно покупают билеты на транспорт в отделениях Почты России

В Москве мужчина ограбил магазин на АЗС, угрожая пистолетом