(University of Illinois at Chicago) A new $1.7 million grant from the National Cancer Institute will enable researchers at the University of Illinois at Chicago to study the fruit and its potential as a treatment for prostate cancer.
(University of Delaware) As the director of NIIMBL, the National Institute for Innovation in Manufacturing Biopharmaceuticals, Kelvin Lee is a changemaker in the biomanufacturing industry. He will received the 2019 Marvin J. Johnson Award in Microbial & Biochemical Technology from the American Chemical Society's Division of Biochemical Technology.
A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells -- which can give rise to every cell type in the body and which can be grown indefinitely in the lab -- into becoming mature T cells capable of killing tumor cells.
Apple orchards surrounded by agricultural lands are visited by a less diverse collection of bee species than orchards surrounded by natural habitats, according to a new Cornell University-led study, published in the journal Science.
(InSilico Medicine, Inc.) Insilico presents its latest results in modern and next-generation AI for Drug Discovery at the R&D Data Intelligence Leaders Forum in Basel, Switzerland, 24 of January.
Coinfection with visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) has been observed in at least 35 countries on four continents and requires special case management. Currently, the World Health Organization recommends AmBisome monotherapy for treatment. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed that a combination therapy of AmBisome and miltefosine is more effective.
In a study published online today in the journal Science, researchers at Albert Einstein College of Medicine, part of Montefiore, prove for the first time that the brain's cerebellum -- long thought to be mainly involved in coordinating movement -- helps control the brain's reward circuitry. The surprising finding indicates that the cerebellum plays a major role in reward processing and social behaviors and could potentially lead to new strategies for treating addiction.
A powerful new technique combines expansion microscopy with lattice light-sheet microscopy for nanoscale imaging of fly and mouse neuronal circuits and their molecular constituents that's roughly 1,000 times faster than other methods.
A new study in Science challenges long-held theories of why a common virus -- cytomegalovirus, or CMV -- can reactivate and become a life-threatening infection in people with a compromised immune system, including blood cancer patients undergoing bone marrow transplantation.
The number of asteroids colliding with the Earth and moon has increased by up to three times over the past 290 million years, according to a major new study involving the University of Southampton. These findings, published in Science challenge our previous understanding of Earth's history.
Using data from the Cassini spacecraft's final orbits, scientists report new measurements of the gravitational field around Saturn and its rings, which allowed them to constrain its internal structure, the depth of its winds, and the mass and age of its rings.
A decade-long analysis of bee activity in apple orchards in New York showed decreased pollination services in some orchards beyond what simple counts of bee number or species richness would predict.
In a mouse model, researchers have identified a potential pathway towards creating effective treatments for Cytomegalovirus, a common, yet potentially lethal viral infection for stem cell transplant patients.
The cerebellum may regulate sociability and reward-driven behavior by controlling the release of dopamine, according to a new study.
If you step on a tack, neurons in your brain will register two things: that there's a piercing physical sensation in your foot, and that it's not pleasant. Now, a team of scientists at Stanford University has identified a bundle of brain cells in mice responsible for the latter -- that is, the negative emotions of pain.
Most of our cells contain an immobile primary cilium. The 'skeleton' of the cilium consists of microtubule doublets, which are 'pairs' of proteins essential for their formation and function. Scientists from UNIGE have developed an in vitro system capable of forming microtubule doublets, and have uncovered the mechanism and dynamics of their assembly. Their study reveals the crucial role of tubulin, a real building block, in preventing the uncontrolled formation of ciliary structures.
Using images and thermal data collected by NASA's Lunar Reconnaissance Orbiter (LRO), Southwest Research Institute scientists and their collaborators have calculated the ages of large lunar craters across the moon to be less than 1 billion years. By comparing the impact history of the moon with Earth's craters over this interval, they discovered that the rate of sizable asteroid collisions has increased by a factor of two to three on both bodies over the last 290 million years.
Animal responses to odors can be learned or innate. The innate capacity to discern between an appetizing and a foul -- i.e., dangerous -- odor is essential, from the start, to guide behavior for survival. Even the youngest animals need to escape predators and find adequate food sources. Until now, little was known about how these innate olfactory responses are hard-wired in the brain.
Researchers have developed a technique to image the brain with unprecedented resolution and speed. Using a combination of expansion microscopy and lattice light-sheet microscopy, they can locate individual neurons, trace connections between them, and visualize organelles inside neurons, over large volumes of brain tissue.
A segment of the multibillion-dollar wearables industry aims to save potential victims from this fate, but a Vanderbilt University engineering professor found a major problem: the devices are measuring the wrong thing.
Researchers at Rush University Medical Center and the MIND Institute at UC Davis have found that mavoglurant, an experimental drug known as an mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome (FXS).
A team of scientists has determined the number of asteroid impacts on the Moon and Earth increased by two to three times starting around 290 million years ago. Previous theories held that there were fewer craters on both objects dating back to before that time because they had disappeared due to erosion. The new findings claim that there were simply fewer asteroid impacts during that earlier period.
Fluorescent tagging of cellular proteins has allowed unprecedentedly detailed images of brain circuits, but imaging neurons and synapses over large areas in fine detail is difficult. Researchers at HHMI, UC Berkeley and MIT have joined two techniques -- expansion microscopy and lattice light-sheet microscopy -- to capture neural circuits, including all synapses, in a whole fly brain in only three days, versus up to 10 years for EM whole-brain imaging. This allows rapid study of brain circuits.
In its last days, the Cassini spacecraft looped between Saturn and its rings so that Earth-based radio telescopes could track the gravitational tug of each. Scientists in Italy and the U.S. have now used these measurements to determine the mass of the rings and estimate its age, which is young: 10-100 million years. This supports the hypothesis that the rings are rubble from a comet or Kuiper Belt object captured late in Saturn's history.
The results of clinical trials conducted in Ethiopia by the Drugs for Neglected Diseases initiative (DNDi), in partnership with Médecins Sans Frontières (MSF), the University of Gondar, and Addis Ababa University, open the way for more effective and safer treatments for people with both HIV and visceral leishmaniasis (VL), a group of patients who have historically suffered from poor treatment options. The results were published today in PLOS Neglected Tropical Diseases.