Elevated plasma concentrations of the uremic toxin asymmetrical dimethylarginine (ADMA) and low plasma concentrations of L-homoarginine are independently associated with cardiovascular events and total mortality. Enzymes degrading ADMA [dimethylaminohydrolase 1 (DDAH1)] and synthesizing L-homoarginine [L-arginine:glycine amidinotransferase (AGAT)] are expressed in human proximal tubule cells. So far, it is not known which transport... Читать дальше...

Use of infrared thermography in the detection of superficial phlebitis in adult intensive care unit patients: A prospective single-center observational study

14.03.2019 00:00

Plos.org

by Frank Doesburg, Joya M. Smit, Wolter Paans, Marisa Onrust, Maarten W. Nijsten, Willem Dieperink

Participation frequency in physical education classes and physical activity and sitting time in Brazilian adolescents

14.03.2019 00:00

Plos.org

by Diego Augusto Santos Silva, Jean-Philippe Chaput, Mark S. Tremblay

Introduction

To examine the association between participation frequency per week in physical education (PE) classes and physical activity (PA) and sitting time levels in adolescents according to the economic development level of the region of residence.

Methods

A cross-sectional study with a sample representative of Brazil was carried out with 12,220 students aged 11–19 years. Participation frequency per week in PE classes... Читать дальше...

Correction: Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells

14.03.2019 00:00

Plos.org

by Congcong Chen, Jason A. Dienhart, Eric C. Bolton

Corn gluten meal induces enteritis and decreases intestinal immunity and antioxidant capacity in turbot (Scophthalmus maximus) at high supplementation levels

14.03.2019 00:00

Plos.org

by Nan Bai, Min Gu, Mingjie Liu, Qian Jia, Shihui Pan, Zhiyu Zhang

Corn gluten meal (CGM) is an important alternative protein source in aquafeed production. However, in turbot (Scophthalmus maximus), CGM could not be effectively utilized because of its low digestibility, the reason for which is still unclear. The purpose of the present study was to investigate and elucidate the cause for the poor utilization of CGM by turbot from the view of gut health. An 8-week feeding trial was conducted... Читать дальше...

Speech-in-noise representation in the aging midbrain and cortex: Effects of hearing loss

14.03.2019 00:00

Plos.org

by Alessandro Presacco, Jonathan Z. Simon, Samira Anderson

Age-related deficits in speech-in-noise understanding pose a significant problem for older adults. Despite the vast number of studies conducted to investigate the neural mechanisms responsible for these communication difficulties, the role of central auditory deficits, beyond peripheral hearing loss, remains unclear. The current study builds upon our previous work that investigated the effect of aging on normal-hearing individuals... Читать дальше...

Correction: Big data and analysis of risk factors for gallbladder disease in the young generation of Korea

14.03.2019 00:00

Plos.org

by Hyung Sun Kim, Seong Kyung Cho, Chang Soo Kim, Joon Seong Park

Correction: Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture

14.03.2019 00:00

Plos.org

by Stuart K. Kim

Correction: Linking root exudates to functional plant traits

14.03.2019 00:00

Plos.org

by Katharina Herz, Sophie Dietz, Karin Gorzolka, Sylvia Haider, Ute Jandt, Dierk Scheel, Helge Bruelheide

Correction: Earlier relapse detection after allogeneic haematopoietic stem cell transplantation by chimerism assays: Digital PCR versus quantitative real-time PCR of insertion/deletion polymorphisms

14.03.2019 00:00

Plos.org

by Jennifer Valero-Garcia, María del Carmen González-Espinosa, Manuel Barrios, Greta Carmona-Antoñanzas, Javier García-Planells, Carlos Ruiz-Lafora, Ainhoa Fuentes-Gálvez, Antonio Jiménez-Velasco

Correction: Prediction of all-cause mortality after liver transplantation using left ventricular systolic and diastolic function assessment

14.03.2019 00:00

Plos.org

by The PLOS ONE Staff

Correction: Improving Pharmacy Staff Knowledge and Practice on Childhood Diarrhea Management in Vietnam: Are Educational Interventions Effective?

14.03.2019 00:00

Plos.org

by Minh Duc Pham, Mona Byrkit, Van Hoang Pham, Trung Pham, Thang Chien Nguyen

Correction: Knowledge of Community General Practitioners and Nurses on Pre-Hospital Stroke Prevention and Treatment in Chongqing, China

14.03.2019 00:00

Plos.org

by Juan Yang, Jie Zhang, Shu Ou, Ni Wang, Jian Wang

Correction: Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox

14.03.2019 00:00

Plos.org

by The PLOS ONE Staff

Retraction: The Tumor Suppressor Role of miR-124 in Osteosarcoma

14.03.2019 00:00

Plos.org

by Shuo Geng, Xiaojun Zhang, Jie Chen, Xing Liu, Hepeng Zhang, Xiaoyan Xu, Yan Ma, Baoxin Li, Yunqi Zhang, Zhenggang Bi, Chenglin Yang, and The PLOS ONE Editors

Retraction: Vector competence of biting midges and mosquitoes for Shuni virus

14.03.2019 00:00

Plos.org

by The PLOS Neglected Tropical Diseases Editors and Staff

Seasonal malaria chemoprevention combined with community case management of malaria in children under 10 years of age, over 5 months, in south-east Senegal: A cluster-randomised trial

14.03.2019 00:00

Plos.org

by Jean Louis A. Ndiaye, Youssoupha Ndiaye, Mamadou S. Ba, Babacar Faye, Maguette Ndiaye, Amadou Seck, Roger Tine, Pape Moussa Thior, Sharanjeet Atwal, Khalid Beshir, Colin Sutherland, Oumar Gaye, Paul Milligan

Новости России

Москва

Ловим лето за хвост: как улететь в отпуск, когда билетов почти нет

Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims

14.03.2019 00:00

Plos.org

by Rishi J. Desai, Ameet Sarpatwari, Sara Dejene, Nazleen F. Khan, Joyce Lii, James R. Rogers, Sarah K. Dutcher, Saeid Raofi, Justin Bohn, John G. Connolly, Michael A. Fischer, Aaron S. Kesselheim, Joshua J. Gagne

Interplay between mitochondria and diet mediates pathogen and stress resistance in Caenorhabditis elegans

14.03.2019 00:00

Plos.org

by Alexey V. Revtovich, Ryan Lee, Natalia V. Kirienko

Diet is a crucial determinant of organismal biology; interactions between the host, its diet, and its microbiota are critical to determining the health of an organism. A variety of genetic and biochemical means were used to assay stress sensitivity in C. elegans reared on two standard laboratory diets: E. coli OP50, the most commonly used food for C. elegans, or E. coli HT115, which is typically used for RNAi-mediated gene knockdown. We... Читать дальше...