Enhanced hydrogen evolution from CuOx-C/TiO2 with multiple electron transport pathways
by Xiuying Huang, Meng Zhang, Runze Sun, Gaoyuan Long, Yifan Liu, Weirong Zhao
Читать дальше...
by Xiuying Huang, Meng Zhang, Runze Sun, Gaoyuan Long, Yifan Liu, Weirong Zhao
Читать дальше...
by Yasuharu Nagano, Keisuke Kobayashi-Yamakawa, Ayako Higashihara, Hiroko Yako-Suketomo
Читать дальше...
by Walter Devillé, Hugo Tempelman
BackgroundHIV-self-testing (HIVST) could be a strategy to get more people tested for HIV in resource limited settings. One of the prerequisites of a successful HIVST programme is the availability of an easy to use, valid HIV-test which is robust against field conditions and procedural errors by untrained lay users.
Methods and findingsThe primary objective of this study was to evaluate the ability of untrained persons to correctly interpret the... Читать дальше...
by Heidi Kucera, Birgit Puschner, Alan Conley, Trish Berger
Production of steroid hormones is complex and dependent upon steroidogenic enzymes, cofactors, receptors, and transporters expressed within a tissue. Collectively, these factors create an environment for tissue-specific steroid hormone profiles and potentially tissue-specific responses to drug administration. Our objective was to assess steroid production, including sulfated steroid metabolites in the boar testis, prostate, and liver following inhibition of aromatase... Читать дальше...
by David Jonathan Duncan, Marietta Scott, Paul Scorer, Craig Barker
Four immunohistochemistry (IHC) diagnostic assays have been approved for tumour PD-L1 protein assessment in the clinic. However, mRNA detection by in situ hybridisation (ISH) could be utilised as an alternative to protein detection. Detecting spatial changes in gene expression provides vital prognostic and diagnostic information, particularly in immune oncology where the phenotype, cellular infiltration and immune activity status may be associated with patient survival.
by Ning Zhang, Peng Gao, Bao Yin, Jiahe Li, Tong Wu, Yu Kuang, Wenxue Wu, Jinxiang Li
Читать дальше...
by Harald Hegen, Anne Zinganell, Michael Auer, Florian Deisenhammer
BackgroundThe presence of ≥3 oligoclonal bands (OCB) in the cerebrospinal fluid (CSF) without corresponding bands in serum represents a definite pathological pattern, whereas the clinical significance of 1–2 CSF bands (borderline pattern) is poorly investigated.
MethodsWe screened 1986 consecutive CSF and serum samples which were collected over a four-year time period and had results of isoelectric focusing (IEF) available. Читать дальше...
by Lena M. Biehl, Debora Garzetti, Fedja Farowski, Diana Ring, Martin B. Koeppel, Holger Rohde, Philippe Schafhausen, Bärbel Stecher, Maria J. G. T. Vehreschild
Читать дальше...
by Olivia A. Obenland, Rong Ma, Sarah R. O’Brien, Anatoli V. Lygin, Dean E. Riechers
Читать дальше...
by Keitaro Makino, Sangyoon Lee, Seongryu Bae, Songee Jung, Yohei Shinkai, Ippei Chiba, Hiroyuki Shimada
Читать дальше...
by Jesus Sainz, Carlos Prieto, Benedicto Crespo-Facorro
Antipsychotics are crucial for the treatment of schizophrenia and contribute to weight gain in psychosis, particularly during early phases. Antipsychotic Induced Weight Gain (AIWG) might contribute to reduce the quality of life, drug compliance and to increase mortality. To characterize sex differences of gene expression related to AIWG, we sequenced total mRNA from blood samples of schizophrenia patients, before and after 3 months of antipsychotic-treatment. Читать дальше...
by Caiyun Zhang, Tongjian Liu, Xun Yuan, Huirun Huang, Gang Yao, Xiaolu Mo, Xue Xue, Haifei Yan
Читать дальше...
by Catherine Lambert Koizumi, Andrew E. Derocher
The abundance of ungulate populations may fluctuate in response to several limiting factors, including climate, diseases, and predation. In the northern Richardson Mountains, Canada, Dall sheep (Ovis dalli dalli) have undergone a major decline in the past decades and predation by grizzly bears (Ursus arctos) and wolves (Canis lupus) was suspected as a leading cause. To better understand the relationship between these three species located in this rugged and remote ecosystem... Читать дальше...
by Davi R. Ortega, Catherine M. Oikonomou, H. Jane Ding, Prudence Rees-Lee, Alexandria , Grant J. Jensen
Читать дальше...
by Aiko Ito, Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Kouichi Shiozawa, Naoya Kawamura, Yuka Yagisawa, Megumi Nariyama, Daisuke Umeki, Yoshiki Nakamura, Satoshi Okumura
Читать дальше...
by Pabitra Saha, Moytrey Chatterjee, Sudeep Ballav, Akash Chowdhury, Nandita Basu, Ardhendu Kumar Maji
Читать дальше...
by Paul J. Fitzgerald, Jessica Y. Yen, Brendon O. Watson
Major depression is a stress-linked disease with significant morbidity and the anesthetic drug ketamine is of growing interest in the treatment of depression, since in responsive individuals a single dose has rapid (within hours) antidepressant effects that can be sustained for over a week in some instances. This combination of fast action and a therapeutic effect that lasts far beyond the drug’s half-life points to a unique mechanism of action. Читать дальше...
by Jason R. Stagno, Ping Yu, Marzena A. Dyba, Yun-Xing Wang, Yu Liu
Due to the paucity of known RNA structures, experimental phasing is crucial for obtaining three-dimensional structures of RNAs by X-ray crystallography. Covalent attachment of heavy atoms to RNAs is one of the most useful strategies to facilitate phase determination. However, this approach is limited by the inefficiency or inability to synthesize large RNAs (>60 nucleotides) site-specifically labeled with heavy atoms using traditional methods. Читать дальше...
by Bao-fang Zhang, YaXin Hu, Xinyan Liu, Zhuo Cheng, Yu Lei, YongMei Liu, Xueke Zhao, Mao Mu, Lei Yu, Ming-liang Cheng
by Mariko Kamata, Hideki Amano, Yoshiya Ito, Tomoe Fujita, Fumisato Otaka, Kanako Hosono, Kouju Kamata, Yasuo Takeuchi, Takehiko Yokomizo, Takao Shimizu, Masataka Majima
by Jesús Ortega, José Martín, Pierre-André Crochet, Pilar López, Jean Clobert
by S. Shanmuga Sundar, N. Kannan, E. Sundaravadivel, Sarang Zsolt, K. S. Mukunthan, J. Manokaran, J. Narendranath, V. P. Kamalakannan, N. P. Kavitha, N. V. Prabhu, N. Balasubramanian
by Claudia Rivera-Rodriguez, Cristiana Toscano, Stephen Resch
by Lance Turtle, Hannah E. Brindle, William Schluter, Brian Faragher, Ajit Rayamajhi, Rajendra Bohara, Santosh Gurung, Geeta Shakya, Sutee Yoksan, Sameer Dixit, Rajesh Rajbhandari, Bimal Paudel, Shailaja Adhikari, Tom Solomon, Mike J. Griffiths
Читать дальше...