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Новости за 18.05.2019

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Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—Phase Ib: Effect of morphology on hemodynamics

Plos.org 
En

by Samuel Voß, Oliver Beuing, Gábor Janiga, Philipp Berg

Background

Image-based blood flow simulations have been increasingly applied to investigate intracranial aneurysm (IA) hemodynamics. However, the acceptance among physicians remains limited due to the high variability in the underlying assumptions and quality of results.

Methods

To evaluate the vessel segmentation as one of the most important sources of error, the international Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH) was announced. Читать дальше...

Seasonal variability in global industrial fishing effort

Plos.org 
En

by Jérôme Guiet, Eric Galbraith, David Kroodsma, Boris Worm

Human beings are the dominant top predator in the marine ecosystem. Throughout most of the global ocean this predation is carried out by industrial fishing vessels, that can now be observed in unprecedented detail via satellite monitoring of Automatic Identification System (AIS) messages. The spatial and temporal distribution of this fishing effort emerges from the coupled interaction of ecological and socio-economic drivers and... Читать дальше...



Shape of ligand immobilized particles dominates and amplifies the macrophage cytokine response to ligands

Plos.org 
En

by Anusha Garapaty, Julie A. Champion

Macrophages aid in clearing synthetic particulates introduced into the body and bridge innate and adaptive immunity through orchestrated secretion of cytokines and chemokines. While the field has made tremendous progress in understanding the effect of particle physicochemical properties on particle-macrophage interactions, it is not known how macrophage functions like cytokine production are affected while presenting active ligands on particles with altered physical properties. Читать дальше...

Catechin attenuates TNF-α induced inflammatory response via AMPK-SIRT1 pathway in 3T3-L1 adipocytes

Plos.org 
En

by An-Wei Cheng, Xin Tan, Jin-Yue Sun, Chun-Mei Gu, Chao Liu, Xu Guo

Chronic inflammation is a fundamental symptom of many diseases. Catechin possesses anti-oxidant and anti-inflammatory properties. However, the mechanism of catechin to prevent inflammation in 3T3-L1 adipocytes caused by TNF-α remains unknown. Therefore, the effects of catechin on the gene expression of cytokines and the activation of cell signals in TNF-α induced 3T3-L1 adipocytes were investigated. The effects of catechin... Читать дальше...

Using an individual-based model to assess common biases in lek-based count data to estimate population trajectories of lesser prairie-chickens

Plos.org 
En

by Beth E. Ross, Daniel S. Sullins, David A. Haukos

Researchers and managers are often interested in monitoring the underlying state of a population (e.g., abundance), yet error in the observation process might mask underlying changes due to imperfect detection and availability for sampling. Additional heterogeneity can be introduced into a monitoring program when male-based surveys are used as an index for the total population. Often, male-based surveys are used for avian species, as males... Читать дальше...

Новости России
Москва

«Она пошла встречаться с подружками в Москве»: новый сериал от Бони и ее дочери


The processivity factor Pol32 mediates nuclear localization of DNA polymerase delta and prevents chromosomal fragile site formation in Drosophila development

Plos.org 
En

by Jingyun Ji, Xiaona Tang, Wen Hu, Keith A. Maggert, Yikang S. Rong

The Pol32 protein is one of the universal subunits of DNA polymerase δ (Pol δ), which is responsible for genome replication in eukaryotic cells. Although the role of Pol32 in DNA repair has been well-characterized, its exact function in genome replication remains obscure as studies in single cell systems have not established an essential role for Pol32 in the process. Here we characterize Pol32 in the context of Drosophila melanogaster development. Читать дальше...


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Польская теннисистка Ига Швентек завоевала свой первый титул на турнире Уимблдон






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