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Transitions in smartphone addiction proneness among children: The effect of gender and use patterns

Plos.org 
En

by Jeng-Tung Chiang, Fong-Ching Chang, Kun-Wei Lee, Szu-Yuan Hsu

Objectives

This study assessed the incidence of transitions in smartphone addiction proneness (SAP) among children and examined the effects of gender, use patterns (social networking sites (SNSs) use and smartphone gaming) and depression on smartphone addiction transitions.

Methods

A representative sample of 2,155 children from Taipei completed longitudinal surveys in both 2015 (5th grade) and 2016 (6th grade). Latent... Читать дальше...

Parameter estimation and mathematical modeling for the quantitative description of therapy failure due to drug resistance in gastrointestinal stromal tumor metastasis to the liver

Plos.org 
En

by Patricio Cumsille, Matías Godoy, Ziomara P. Gerdtzen, Carlos Conca

In this work we develop a general mathematical model and devise a practical identifiability approach for gastrointestinal stromal tumor (GIST) metastasis to the liver, with the aim of quantitatively describing therapy failure due to drug resistance. To this end, we have modeled metastatic growth and therapy failure produced by resistance to two standard treatments based on tyrosine kinase inhibitors (Imatinib and Sunitinib)... Читать дальше...

Association of the ACTN3 R577X (rs1815739) polymorphism with elite power sports: A meta-analysis

Plos.org 
En

by Phuntila Tharabenjasin, Noel Pabalan, Hamdi Jarjanazi

Objective

The special status accorded to elite athletes stems from their uncommon genetic potential to excel in world-class power sports (PS). Genetic polymorphisms have been reported to influence elite PS status. Reports of associations between the α-actinin-3 gene (ACTN3) R577X polymorphism and PS have been inconsistent. In light of new published studies, we perform a meta-analysis to further explore the roles of this polymorphism in PS performance among elite athletes. Читать дальше...

Do street-level scene perceptions affect housing prices in Chinese megacities? An analysis using open access datasets and deep learning

Plos.org 
En

by Xiao Fu, Tianxia Jia, Xueqi Zhang, Shanlin Li, Yonglin Zhang

Many studies have explored the relationship between housing prices and environmental characteristics using the hedonic price model (HPM). However, few studies have deeply examined the impact of scene perception near residential units on housing prices. This article used house purchasing records from FANG.com and open access geolocation data (including massive street view pictures, point of interest (POI) data and road network... Читать дальше...



RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries

Plos.org 
En

by Li Zhu, Susan E. Liao, Yiwei Ai, Ryuya Fukunaga

RNA methyltransferases post-transcriptionally add methyl groups to RNAs, which can regulate their fates and functions. Human BCDIN3D (Bicoid interacting 3 domain containing RNA methyltransferase) has been reported to specifically methylate the 5′-monophosphates of pre-miR-145 and cytoplasmic tRNAHis. Methylation of the 5′-monophosphate of pre-miR-145 blocks its cleavage by the miRNA generating enzyme Dicer, preventing generation of miR-145. Читать дальше...

Using sibling data to explore the impact of neighbourhood histories and childhood family context on income from work

Plos.org 
En

by Lina Hedman, David Manley, Maarten van Ham

Previous research has reported evidence of intergenerational transmissions of neighbourhood status and social and economic outcomes later in life. Research also shows neighbourhood effects on adult incomes of both childhood and adult neighbourhood experiences. However, these estimates of neighbourhood effects may be biased because confounding factors originating from the childhood family context. It is likely that part of the neighbourhood effects observed for adults... Читать дальше...

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