by Shixiu Wei, Zhenhui Lu, Yunfeng Zou, Xiao Lin, Cuiwu Lin, Buming Liu, Li Zheng, Jinmin Zhao
by Emmanuel Edwar Siddig, Najwa Adam Mhmoud, Sahar Mubarak Bakhiet, Omnia Babekir Abdallah, Salwa Osman Mekki, Nadia I. El Dawi, Wendy Van de Sande, Ahmed Hassan Fahal
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by Zuzana Sekeyová, Monika Danchenko, Peter Filipčík, Pierre Edouard Fournier
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by Aline Kuhn Sbruzzi Pasquali, Rafael Antunes Baggio, Walter Antonio Boeger, Nilsa González-Britez, Deborah Carbonera Guedes, Enmanuel Céspedes Chaves, Vanete Thomaz-Soccol
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by Guillermo Moscatelli, Samanta Moroni, Facundo García Bournissen, Nicolás González, Griselda Ballering, Alejandro Schijman, Ricardo Corral, Margarita Bisio, Héctor Freilij, Jaime Altcheh
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by Jan O. Lundström, Jenny C. Hesson, Martina L. Schäfer, Örjan Östman, Torsten Semmler, Michaël Bekaert, Manfred Weidmann, Åke Lundkvist, Martin Pfeffer
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by Julia H. Kemis, Vanessa Linke, Kelsey L. Barrett, Frederick J. Boehm, Lindsay L. Traeger, Mark P. Keller, Mary E. Rabaglia, Kathryn L. Schueler, Donald S. Stapleton, Daniel M. Gatti, Gary A. Churchill, Daniel Amador-Noguez, Jason D. Russell, Brian S. Yandell, Karl W. Broman, Joshua J. Coon, Alan D. Attie, Federico E. Rey
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by Fu Xu, Anders S. Byström, Marcus J. O. Johansson
The Elongator complex promotes formation of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) side-chains on uridines at the wobble position of cytosolic eukaryotic tRNAs. In all eukaryotic organisms tested to date, the inactivation of Elongator not only leads to the lack of mcm5/ncm5 groups in tRNAs, but also a wide variety of additional phenotypes. Although the phenotypes are most likely caused by a translational defect induced... Читать дальше...
by Jingyuan Fu, Folkert Kuipers
by José Antonio Villaécija-Aguilar, Maxime Hamon-Josse, Samy Carbonnel, Annika Kretschmar, Christian Schmid, Corinna Dawid, Tom Bennett, Caroline Gutjahr
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by Aubin Fleiss, Samuel O'Donnell, Téo Fournier, Wenqing Lu, Nicolas Agier, Stéphane Delmas, Joseph Schacherer, Gilles Fischer
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by Alison Wood, Sophie E. Irving, Daniel J. Bennison, Rebecca M. Corrigan
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by Hongliang Wang, Siyi Guo, Xin Qiao, Jianfei Guo, Zuliang Li, Yusen Zhou, Shenglong Bai, Zhiyong Gao, Daojie Wang, Pengcheng Wang, David W. Galbraith, Chun-Peng Song
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by Laura W. Pomeroy, Hyeyoung Kim, Ningchuan Xiao, Mark Moritz, Rebecca Garabed
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by Moshe Glickman, Orian Sharoni, Dino J. Levy, Ernst Niebur, Veit Stuphorn, Marius Usher
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by Diego Pereira Botelho, Kathleen Curran, Madeleine M. Lowery
This study presents a modelling framework in which information on muscle fiber direction and orientation during contraction is derived from diffusion tensor imaging (DTI) and incorporated in a computational model of the surface electromyographic (EMG) signal. The proposed model makes use of the principle of reciprocity to simultaneously calculate the electric potentials produced at the recording electrode by charges distributed... Читать дальше...
by Vincent Miele, Christian Guill, Rodrigo Ramos-Jiliberto, Sonia Kéfi
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by Jacob Bradford, Dimitri Perrin
The popularity of CRISPR-based gene editing has resulted in an abundance of tools to design CRISPR-Cas9 guides. This is also driven by the fact that designing highly specific and efficient guides is a crucial, but not trivial, task in using CRISPR for gene editing. Here, we thoroughly analyse the performance of 18 design tools. They are evaluated based on runtime performance, compute requirements, and guides generated. To achieve this, we implemented a method... Читать дальше...
by Patricia D. Koman, Veena Singla, Juleen Lam, Tracey J. Woodruff
The 2016 Frank Lautenberg Chemical Safety for the 21st Century Act (Lautenberg TSCA) amended the 1976 Toxic Substances Control Act (TSCA) to mandate protection of susceptible and highly exposed populations. Program implementation entails a myriad of choices that can lead to different degrees of public health protections. Well-documented exposures to multiple industrial chemicals occur from air, soil, water, food, and products in our workplaces, schools, and homes. Читать дальше...
by Arden Perkins, Dan A. Tudorica, Manuel R. Amieva, S. James Remington, Karen Guillemin
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You can do anything in a dress! At least, that is what Outdoor Voices wants you to believe when wearing The Exercise Dress. If you’re not familiar with the dress, it is a piece of activewear that looks like a dress on first glance but can actually handle a light or vigorous workout.
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The cycling hero revealed murders were common on the estate where he grew up
TV's favourite tough guy had to be saved by medics after the frightening encounter
Boris Johnson has said Brexit talks with the European Union will be stepped up in the coming weeks in a bid to secure a new deal.