by Alexander F. Flynn, M. Gordon Joyce, Rebekah T. Taylor, Sasisekhar Bennuru, Alyssa R. Lindrose, Spencer L. Sterling, C. Paul Morris, Thomas B. Nutman, Edward Mitre
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by Ricardo Dias Portela, Rodrigo Pedro Soares, Gabriela Porfírio Passos, Daniela Farias Larangeira, Thiago Doria Barral, Julia Ramos Sampaio, Marcos F. Bernardo, Edneia Venâncio Alves-Sobrinho, Maria Terezinha Bahia, Flaviane Alves Pinho, Stella Maria Barrouin-Melo
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by Carolina Rosadas, Jennifer H. Tosswill, Richard Tedder, Graham P. Taylor
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by Piero Ruscitti, Francesco Masedu, Saverio Alvaro, Paolo Airò, Norma Battafarano, Luca Cantarini, Francesco Paolo Cantatore, Giorgio Carlino, Virginia D'Abrosca, Micol Frassi, Bruno Frediani, Daniela Iacono, Vasiliki Liakouli, Roberta Maggio, Rita Mulè, Ilenia Pantano, Immacolata Prevete, Luigi Sinigaglia, Marco Valenti, Ombretta Viapiana, Paola Cipriani, Roberto Giacomelli
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by Anne Ahrendt Bjerregaard, Thorhallur Ingi Halldorsson, Inge Tetens, Sjurdur Frodi Olsen
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by Zhao Peng, Ely Oliveira-Garcia, Guifang Lin, Ying Hu, Melinda Dalby, Pierre Migeon, Haibao Tang, Mark Farman, David Cook, Frank F. White, Barbara Valent, Sanzhen Liu
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by Babatunde Ekundayo, Franziska Bleichert
In all kingdoms of life, DNA is used to encode hereditary information. Propagation of the genetic material between generations requires timely and accurate duplication of DNA by semiconservative replication prior to cell division to ensure each daughter cell receives the full complement of chromosomes. DNA synthesis of daughter strands starts at discrete sites, termed replication origins, and proceeds in a bidirectional manner until all genomic DNA is replicated. Читать дальше...
by Robert L. Baker, Wen Fung Leong, Marcus T. Brock, Matthew J. Rubin, R. J. Cody Markelz, Stephen Welch, Julin N. Maloof, Cynthia Weinig
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by Gregory S. Barsh, Gregory P. Copenhaver, Elapulli Sankaranarayanan Prakash, Daniela C. Zarnescu
by Qanita Bani Baker, Maryam S. Nuser
Bioinformatics plays a key role in supporting the life sciences. In this work, we examine bioinformatics in Jordan, beginning with the current status of bioinformatics education and research, then exploring the challenges of advancing bioinformatics, and finally looking to the future for how Jordanian bioinformatics research may develop.
by Kaiser Niknam, Amir Akbarian, Kelsey Clark, Yasin Zamani, Behrad Noudoost, Neda Nategh
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by Eberhard O. Voit
The scientific method has been guiding biological research for a long time. It not only prescribes the order and types of activities that give a scientific study validity and a stamp of approval but also has substantially shaped how we collectively think about the endeavor of investigating nature. The advent of high-throughput data generation, data mining, and advanced computational modeling has thrown the formerly undisputed, monolithic status of the scientific method into turmoil. Читать дальше...
by Dan Sholler, Igor Steinmacher, Denae Ford, Mara Averick, Mike Hoye, Greg Wilson
by Alexander D. Becker, Amy Wesolowski, Ottar N. Bjørnstad, Bryan T. Grenfell
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by Christoph Schmal, Daisuke Ono, Jihwan Myung, J. Patrick Pett, Sato Honma, Ken-Ichi Honma, Hanspeter Herzel, Isao T. Tokuda
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by Bruno Burlando, Franco Blanchini, Giulia Giordano
We performed a mathematical analysis of the dynamic control loops regulating the vasomotor tone of vascular smooth muscle, blood volume, and mean arterial pressure, which involve the arginine vasopressin (AVP) system, the atrial natriuretic peptide system (ANP), and the renin-angiotensin-aldosterone system (RAAS). Our loop analysis of the AVP-ANP-RAAS system revealed the concurrent presence of two different regulatory mechanisms, which perform the same qualitative function... Читать дальше...
by Anton V. Chizhov, Artyom V. Zefirov, Dmitry V. Amakhin, Elena Yu. Smirnova, Aleksey V. Zaitsev
by Beerend H. J. Winkelman, Marcus H. C. Howlett, Maj-Britt Hölzel, Coen Joling, Kathryn H. Fransen, Gobinda Pangeni, Sander Kamermans, Hiraki Sakuta, Masaharu Noda, Huibert J. Simonsz, Maureen A. McCall, Chris I. De Zeeuw, Maarten Kamermans
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by Thomas Decramer, Elsie Premereur, Mats Uytterhoeven, Wim Van Paesschen, Johannes van Loon, Peter Janssen, Tom Theys
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by Jun Liu, Ming Gao, Michael Nipper, Janice Deng, Francis E. Sharkey, Randy L. Johnson, Howard C. Crawford, Yidong Chen, Pei Wang
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by Reshef Tal, Shafiq Shaikh, Pallavi Pallavi, Aya Tal, Francesc López-Giráldez, Fang Lyu, Yuan-Yuan Fang, Shruti Chinchanikar, Ying Liu, Harvey J. Kliman, Myles Alderman III, Nicola Pluchino, Jehanzeb Kayani, Ramanaiah Mamillapalli, Diane S. Krause, Hugh S. Taylor
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by Melanie Falgairolle, Michael J. O’Donovan
In the mouse spinal cord, V1 interneurons are a heterogeneous population of inhibitory spinal interneurons that have been implicated in regulating the frequency of the locomotor rhythm and in organizing flexor and extensor alternation. By introducing archaerhodopsin into engrailed-1-positive neurons, we demonstrate that the function of V1 neurons in locomotor-like activity is more complex than previously thought. In the whole cord, V1 hyperpolarization... Читать дальше...
Photo by Chris Unger/Zuffa LLC/Zuffa LLC via Getty Images
“You’re talking about it right now. There you go, you just answered it yourself.”
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Way back in 2017 (nearly ancient history in the world of energy tech) the United Kingdom was smashing its own solar power records and celebrating “the latest in a series of records for solar, which has grown from almost nothing seven years ago to 12GW of capacity today” as reported by the Guardian. The article went on to enumerate some of these milestones, including the fact that “In April this year [2017], Britain achieved its first-ever full working day without coal power since it started burning the fuel in 1882... Читать дальше...