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Новости за 16.10.2019

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Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age

Plos.org 
En

by Rocío Belinchón, Lucie Hemrová, Zuzana Münzbergová

Many grasslands have disappeared over the last century as a result of anthropogenic land use intensification, while new patches are emerging through abandonment of arable fields. Here, we compared species (SD), functional (FD) and phylogenetic (PD) (alpha) diversity among 272 dry grassland patches of two age-classes: old and new, with the new patches being dry grasslands established on previous intensively managed fields during the last 30 years. Читать дальше...



Egg yolk-free cryopreservation of bull semen

Plos.org 
En

by Muhammad Anzar, Kosala Rajapaksha, Lyle Boswall

Egg yolk is a common ingredient of mammalian semen extender to protect sperm against initial cold shock. However, egg yolk has biosecurity risks. Our main objectives were to cryopreserve bull semen without egg yolk using exogenous cholesterol and to study the protective role of glycerol in egg yolk-free semen extender. Other objectives were to compare protein profiles and in vitro fertilization potential of bull sperm frozen with and without egg yolk. Читать дальше...

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TAPES: A tool for assessment and prioritisation in exome studies

Plos.org 
En

by Alexandre Xavier, Rodney J. Scott, Bente A. Talseth-Palmer

Next-generation sequencing continues to grow in importance for researchers. Exome sequencing became a widespread tool to further study the genomic basis of Mendelian diseases. In an effort to identify pathogenic variants, reject benign variants and better predict variant effects in downstream analysis, the American College of Medical Genetics (ACMG) published a set of criteria in 2015. While there are multiple publicly available... Читать дальше...

Experimental evolution reveals a general role for the methyltransferase Hmt1 in noise buffering

Plos.org 
En

by Shu-Ting You, Yu-Ting Jhou, Cheng-Fu Kao, Jun-Yi Leu

Cell-to-cell heterogeneity within an isogenic population has been observed in prokaryotic and eukaryotic cells. Such heterogeneity often manifests at the level of individual protein abundance and may have evolutionary benefits, especially for organisms in fluctuating environments. Although general features and the origins of cellular noise have been revealed, details of the molecular pathways underlying noise regulation remain elusive. Читать дальше...

Somatosensory cortex participates in the consolidation of human motor memory

Plos.org 
En

by Neeraj Kumar, Timothy F. Manning, David J. Ostry

Newly learned motor skills are initially labile and then consolidated to permit retention. The circuits that enable the consolidation of motor memories remain uncertain. Most work to date has focused on primary motor cortex, and although there is ample evidence of learning-related plasticity in motor cortex, direct evidence for its involvement in memory consolidation is limited. Learning-related plasticity is also observed in somatosensory cortex... Читать дальше...


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