Добавить новость
ru24.net
News in English
Календарь
Ноябрь
2019
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30

Новости за 12.11.2019

1510501005009869879889899909919921000 >>>

Affective disorders in the elderly in different European countries: Results from the MentDis_ICF65+ study

Plos.org 
En

by Sylke Andreas, Maria Dehoust, Jana Volkert, Holger Schulz, Susanne Sehner, Anna Suling, Karl Wegscheider, Berta Ausín, Alessandra Canuto, Mike J. Crawford, Chiara Da Ronch, Luigi Grassi, Yael Hershkovitz, Manuel Muñoz, Alan Quirk, Ora Rotenstein, Ana Belén Santos-Olmo, Arieh Y. Shalev, Kerstin Weber, Hans-Ulrich Wittchen, Martin Härter

Читать дальше...



How to design a dose-finding study on combined agents: Choice of design and development of R functions

Plos.org 
En

by Monia Ezzalfani

Background

In oncology, the aim of dose-finding phase I studies is to find the maximum tolerated dose for further studies. The use of combinations of two or more agents is increasing. Several dose-finding designs have been proposed for this situation. Numerous publications have however pointed out the complexity of evaluating therapies in combination due to difficulties in choosing between different designs for an actual trial, as well as complications related to their implementation and application in practice. Читать дальше...

Arthroscopic release for frozen shoulder: Does the timing of intervention and diabetes affect outcome?

Plos.org 
En

by Yu-De Su, Tien-Ching Lee, Yu-Chuan Lin, Shen-Kai Chen

Purpose

To evaluate the effect of timing of arthroscopic release and manipulation under anesthesia for frozen shoulder in patients with diabetes and non-diabetes.

Methods

One hundred and twenty-seven patients with frozen shoulder were included in the study. Each patient was assigned to: 1) one of four groups according to the duration from symptom onset to surgery (group A: ≤3 months; group B: 3–6 months; group C: 6–12 months; group D... Читать дальше...

Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure

Plos.org 
En

by Oluwole Ojo Alese, Musa V. Mabandla

The impact of febrile seizure has been shown to transcend immediate generation with the alteration of glutamatergic pathway being implicated. However, transgenerational effects of this neurological disorder particularly prolonged febrile seizure (PFS) on neurobehavioral study and methylation profile is unknown. We therefore hypothesized that transgenerational impact of prolonged febrile seizure is dependent on methylation of hippocampal mGluR1 gene.... Читать дальше...

Determinants of preterm birth among mothers who gave birth at public hospitals in the Amhara region, Ethiopia: A case-control study

Plos.org 
En

by Abay Woday, Muluken Dessalegn Muluneh, Samiha Sherif

Background

Preterm birth (PTB) is a public health issue worldwide. In developing nations, like Ethiopia, PTB is under reported and underestimated. However, it is the leading cause of neonatal and under-five mortality in Ethiopia. Besides, limited and non-comparative research studies to date has been conducted in the country to address the prevalence of PTB. Therefore, this study aims to determine predictors of PTB.

Methods

Hospital-based... Читать дальше...

Новости России

Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs

Plos.org 
En

by Rensu P. Theart, Ben Loos, Thomas R. Niesler

The qualitative analysis of colocalisation in fluorescence microscopy is of critical importance to the understanding of biological processes and cellular function. However, the degree of accuracy achieved may differ substantially when executing different yet commonly utilized colocalisation analyses. We propose a novel biological visual analysis method that determines the correlation within the fluorescence intensities and subsequently uses... Читать дальше...

Spatial and temporal variations in female size at maturity of a Southern Rock Lobster (Jasus edwardsii) population: A likely response to climate change

Plos.org 
En

by Lachlan J. McLeay, Mark J. Doubell, Adrian J. Linnane

The size at which sexual maturity is reached is a key population parameter used to guide the setting of minimum legal size limits in fisheries. Understanding spatial and temporal variations in size at maturity is fundamental to management because the relationship between size at maturity and minimum legal size limits affects the fraction of the mature population biomass that is harvested, and resulting egg production, larval settlement and recruitment. Читать дальше...


Спорт в России и мире

Новости спорта


Новости тенниса






Спонсорский контент

Все новости smi24.net