by William R. Nardi, Abigail Harrison, Frances B. Saadeh, Julie Webb, Anna E. Wentz, Eric B. Loucks
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by Ariane C. Scheuren, Gisela A. Kuhn, Ralph Müller
In vivo micro-CT has already been used to monitor microstructural changes of bone in mice of different ages and in models of age-related diseases such as osteoporosis. However, as aging is accompanied by frailty and subsequent increased sensitivity to external stimuli such as handling and anesthesia, the extent to which longitudinal imaging can be applied in aging studies remains unclear. Consequently, the potential of monitoring individual... Читать дальше...
by Yuji Ishida, Chihiro Yamasaki, Hiroko Iwanari, Hisahiko Yamashita, Yuko Ogawa, Ami Yanagi, Suzue Furukawa, Yuha Kojima, Kazuaki Chayama, Junichi Kamiie, Chise Tateno
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by Min-Su Kim, Seongmin An, Songwan Jin, Taehoen Kim, Tack-Kyun Kwon
Injection laryngoplasty (IL) has been used to treat various types of glottal insufficiency. The precise volume and location of the injected materials impact the outcomes. However, exactly how increasing volumes of material are distributed is unknown. In fact, the amount of IL material required to medialize a vocal cord tends to be determined empirically. Thus, the goal of this study was to investigate the pattern of IL material... Читать дальше...
by Seong Eun Lee, Hyung Bin Lim, Yong Il Shin, Cheon Kuk Ryu, Woo Hyuk Lee, Jung-Yeul Kim
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by Olivia R. Stockly, Audrey E. Wolfe, Gretchen J. Carrougher, Barclay T. Stewart, Nicole S. Gibran, Steven E. Wolf, Kara McMullen, Alyssa M. Bamer, Karen Kowalske, William G. Cioffi, Ross Zafonte, Jeffrey C. Schneider, Colleen M. Ryan
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by Thomas Salaets, Bieke Tack, André Gie, Benjamin Pavie, Nikhil Sindhwani, Julio Jimenez, Yannick Regin, Karel Allegaert, Jan Deprest, Jaan Toelen
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by Christian Tackenberg, Luka Kulic, Roger M. Nitsch
Familial forms of Alzheimer’s disease (AD) are caused by mutations in the presenilin genes or in the gene encoding for the amyloid precursor protein (APP). Proteolytic cleavage of APP generates the β-amyloid peptide (Aβ), which aggregates into amyloid plaques, one of the major hallmarks of AD. APP mutations within the Aβ sequence, so-called intra-Aβ mutations, cluster around position E693 of APP, which corresponds to position E22 in the Aβ sequence. Читать дальше...
by Adam Boethius, Hege Hollund, Johan Linderholm, Santeri Vanhanen, Mathilda Kjällquist, Ola Magnell, Jan Apel
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by Ahmed Faisal Sumit, Anindya Das, Ishtiaq Hossain Miraj, Debasish Bhowmick
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by Manuel Vázquez-Marrufo, Rocío Caballero-Díaz, Rubén Martín-Clemente, Alejandro Galvao-Carmona, Javier J. González-Rosa
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by Prasanna M. Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A. Whelan, Hisatsugu Maekawa, Uma M. Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V. Gonzalez, James Garifallou, Shinya Ohashi, Andres J. Klein-Szanto, Clementina A. Mesaros, Ian A. Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A. Baur, Hiroshi Nakagawa
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by Tyler Jones, Naava Naslavsky, Steve Caplan
Upon internalization, receptors are trafficked to sorting endosomes (SE) where they undergo sorting and are then packaged into budding vesicles that undergo fission and transport within the cell. Eps15 Homology Domain Protein 1 (EHD1), the best-characterized member of the Eps15 Homology Domain Protein (EHD) family, has been implicated in catalyzing the fission process that releases endosome-derived vesicles for recycling to the plasma membrane. Читать дальше...
by Haroldo V. Ribeiro, Andre S. Sunahara, Jack Sutton, Matjaž Perc, Quentin S. Hanley
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by Rajabu Hussein Mnkugwe, Omary Minzi, Safari Kinung’hi, Appolinary Kamuhabwa, Eleni Aklillu
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by Marie-Marie Olive, Thierry Baldet, James Devillers, Johanna Fite, Marie-Claire Paty, Christophe Paupy, Philippe Quénel, Elsa Quillery, Jocelyn Raude, Jean-Paul Stahl, Marie Thiann-Bo-Morel, David Roiz
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by Christian Groß, Chiara Bortoluzzi, Dick de Ridder, Hendrik-Jan Megens, Martien A. M. Groenen, Marcel Reinders, Mirte Bosse
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by J. Kyle Medley, Jonathan Teo, Sung Sik Woo, Joseph Hellerstein, Rahul Sarpeshkar, Herbert M. Sauro
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by Aditi Roy, Marta Varela, Henry Chubb, Robert MacLeod, Jules C. Hancox, Tobias Schaeffter, Oleg Aslanidi
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by Camila P. E. de Souza, Mirela Andronescu, Tehmina Masud, Farhia Kabeer, Justina Biele, Emma Laks, Daniel Lai, Patricia Ye, Jazmine Brimhall, Beixi Wang, Edmund Su, Tony Hui, Qi Cao, Marcus Wong, Michelle Moksa, Richard A. Moore, Martin Hirst, Samuel Aparicio, Sohrab P. Shah
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by Max Mueller, Veronica Egger
The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition. As a case in point for dendritic transmitter release, rat granule cell dendrites are highly excitable, featuring local Na+ spine spikes and global Ca2+- and Na+-spikes. To investigate the transition from local to global signaling, we performed holographic, simultaneous 2-photon... Читать дальше...
Summary List Placement
Sperm count refers to the amount of sperm per milliliter of semen. Measuring sperm count is usually part of a sperm analysis that also examines the shape of sperm and their motility. All these factors can play a role in a man's fertility.
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Natural gas has often been vilified as just another fossil fuel contributing to the climate crisis. While gas-fired power generation and the natural gas value chain do emit greenhouse gases, natural gas burns cleaner than other fossil fuels, most notably coal, and can play a major role in replacing coal-fired power generation, immediately contributing to lower emissions from the electricity sector. Natural gas also has an important role to play in helping power grids with flexible and reliable... Читать дальше...
The subject of the project was the designing of a residential unit of approximately 300 square meters area for the parents of a family, and four units of 150 square meters area for children and a possible surplus in the construction license on a 510 square meter land for sale.