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2021

Новости за 15.02.2021

Fragments vs Notum, three ways

Practicalfragments.blogspot.com 

The Wnt signaling pathway has been implicated in multiple diseases, from Alzheimer’s to cancer to osteoporosis. To be able to bind receptors, Wnt proteins must be post-translationally modified with a palmitoleate group. The carboxylesterase Notum removes this group, shutting of signaling. Thus, inhibitors of Notum could maintain Wnt activity. In two J. Med. Chem. papers, E. Yvonne Jones (University of Oxford), Paul Fish (University College London), and collaborators describe three series of inhibitors derived from fragments. Читать дальше...

CEO of Greek bank bailout fund resigns

Kathimerini 

The Chief Executive of Greece’s bank bailout fund (HFSF), Martin Czurda, submitted his resignation on Monday, after a little more than three years at the post.

Thousands of Republicans drop party affiliation following Capitol riot

CBSNews.com 

Thousands of registered Republicans in states across the country have opted to change their party affiliation and leave the GOP in the weeks following the insurrection at the Capitol. Army veteran Juan Nunez is one of the former Republicans who recently left the party and he joins CBSN to explain why.

The impact of Trump's second acquittal on both parties

CBSNews.com 

The Senate acquitted former President Trump of charges he incited the deadly insurrection at the U.S. Capitol. CBSN's Vladimir Duthiers spoke with Antjuan Seawright, a CBS News political contributor and a Democratic strategist, and Kevin Sheridan, a founding partner of Protean Public Affairs and a former Republican National Committee spokesman, about the impact the acquittal will have on both parties moving forward.



Multiple states declare emergencies as an arctic blast brings historic winter weather

CBSNews.com 

A severe winter storm is blasting much of the U.S. with heavy snow, freezing rain, ice and some of the coldest temperatures in years. Several states have declared emergencies as officials warn residents to stay home. CBS News meteorologist and climate specialist Jeff Berardelli joins "CBSN AM" to discuss the latest.

Empty stores and offices on the rise in Nagoya

The Japan Times 

Nagoya’s central district is seeing more empty stores and offices as the COVID-19 pandemic has led to an increase in teleworking and almost no inbound ...

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Москва

Глобальное масштабирование: компания «Газинформсервис» участвует в обсуждении применения электронной транспортной накладной с ЕЭК ООН



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Андрей Рублёв

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