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2021

Новости за 22.07.2021

The complete mitochondrial genome of Cycas debaoensis revealed unexpected static evolution in gymnosperm species

Plos.org 

by Sadaf Habib, Shanshan Dong, Yang Liu, Wenbo Liao, Shouzhou Zhang

Mitochondrial genomes of vascular plants are well known for their liability in architecture evolution. However, the evolutionary features of mitogenomes at intra-generic level are seldom studied in vascular plants, especially among gymnosperms. Here we present the complete mitogenome of Cycas debaoensis, an endemic cycad species to the Guangxi region in southern China. In addition to assemblage of draft mitochondrial genome... Читать дальше...

Cuba—U.S. scientific collaboration: Beyond the embargo

Plos.org 

by Guillermo Armando Ronda-Pupo

Cuba and the U.S. have the oldest Academies of Sciences outside Europe. Both countries have a long history of scientific collaboration that dates to the 1800s. Both scientific communities also share geographical proximity and common scientific research interests mainly in Biotechnology, Meteorology, and Public Health research. Despite these facts, scientists from both nations face serious barriers to cooperation raised by the U.S. embargo established in 1961 that prohibits exchanges with Cuba. Читать дальше...



An evaluation of the chemical content and microbiological contamination of Anatolian bee venom

Plos.org 

by Aslı Elif Tanuğur-Samanc, Meral Kekeçoğlu

Bee venom is a natural substance produced by worker bees. The aim of this research paper is to determine the characteristics of Anatolian bee venom by evaluating its chemical content and microbiological properties. Physical, chemical and microbiological analyses were performed on 25 bee venom samples from different areas of Anatolia, Turkey. Data obtained by 3-replicate studies were evaluated with normality and one-way and two-way ANOVA / Tukey tests. Читать дальше...

FFPE samples from cavitational ultrasonic surgical aspirates are suitable for RNA profiling of gliomas

Plos.org 

by Cristina Alenda, Estefanía Rojas, Luis M. Valor

During surgical procedures for gliomas, tissue material obtained from cavitational ultrasonic surgical aspirators (CUSAs) is generally discarded but can actually exceed the amount and quality of certain tumour core resections (TCRs). Despite reports indicating the suitability of CUSA-derived material for diagnosis and research, its use is still marginal. We extended these conclusions to formalin-fixed, paraffin-embedded (FFPE) samples, the... Читать дальше...

Addressing antimicrobial resistance by improving access and quality of care—A review of the literature from East Africa

Plos.org 

by Kathrin Loosli, Alicia Davis, Adrian Muwonge, Tiziana Lembo

Universal access to healthcare, including quality medicines, is a fundamental human right but is still out of reach for many in low- and middle-income countries (LMICs). An existing framework capturing variability of access to healthcare in low-resource settings includes the 5 dimensions: availability, accessibility, affordability, adequacy, and acceptability. This framework encompasses key components, including health infrastructure... Читать дальше...

Новости России
Москва

Возобновление маршрута: Пхеньян и Москва снова связаны поездом


Fission yeast Rad8/HLTF facilitates Rad52-dependent chromosomal rearrangements through PCNA lysine 107 ubiquitination

Plos.org 

by Jie Su, Ran Xu, Piyusha Mongia, Naoko Toyofuku, Takuro Nakagawa

Gross chromosomal rearrangements (GCRs), including translocation, deletion, and inversion, can cause cell death and genetic diseases such as cancer in multicellular organisms. Rad51, a DNA strand exchange protein, suppresses GCRs by repairing spontaneous DNA damage through a conservative way of homologous recombination, gene conversion. On the other hand, Rad52 that catalyzes single-strand annealing (SSA) causes GCRs using homologous sequences. Читать дальше...

Optimizing testing for COVID-19 in India

Plos.org 

by Philip Cherian, Sandeep Krishna, Gautam I. Menon

COVID-19 testing across India uses a mix of two types of tests. Rapid Antigen Tests (RATs) are relatively inexpensive point-of-care lateral-flow-assay tests, but they are also less sensitive. The reverse-transcriptase polymerase-chain-reaction (RT-PCR) test has close to 100% sensitivity and specificity in a laboratory setting, but delays in returning results, as well as increased costs relative to RATs, may vitiate this advantage. India-wide... Читать дальше...

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities

Plos.org 

by Liliana Angeles-Martinez, Vassily Hatzimanikatis

The metabolic capabilities of the species and the local environment shape the microbial interactions in a community either through the exchange of metabolic products or the competition for the resources. Cells are often arranged in close proximity to each other, creating a crowded environment that unevenly reduce the diffusion of nutrients. Herein, we investigated how the crowding conditions and metabolic variability among cells shape the dynamics of microbial communities. Читать дальше...

The influence of the crowding assumptions in biofilm simulations

Plos.org 

by Liliana Angeles-Martinez, Vassily Hatzimanikatis

Microorganisms are frequently organized into crowded structures that affect the nutrients diffusion. This reduction in metabolite diffusion could modify the microbial dynamics, meaning that computational methods for studying microbial systems need accurate ways to model the crowding conditions. We previously developed a computational framework, termed CROMICS, that incorporates the effect of the (time-dependent) crowding conditions on the... Читать дальше...


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