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Новости за 23.02.2022

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Survival analysis of cancer patients using a new extended Weibull distribution

Plos.org 
En

by Hadeel S. Klakattawi

One of the most important applications of statistical analysis is in health research and applications. Cancer studies are mostly required special statistical considerations in order to find the appropriate model for fitting the survival data. Existing classical distributions rarely fit such data well and an increasing interest has been shown recently in developing more flexible distributions by introducing some additional parameters to the basic model. In this paper... Читать дальше...



Bilinguals’ speech perception in noise: Perceptual and neural associations

Plos.org 
En

by Dana Bsharat-Maalouf, Hanin Karawani

The current study characterized subcortical speech sound processing among monolinguals and bilinguals in quiet and challenging listening conditions and examined the relation between subcortical neural processing and perceptual performance. A total of 59 normal-hearing adults, ages 19–35 years, participated in the study: 29 native Hebrew-speaking monolinguals and 30 Arabic-Hebrew-speaking bilinguals. Auditory brainstem responses to speech sounds were... Читать дальше...

Comparative outcomes of combined corticosteroid and remdesivir therapy with corticosteroid monotherapy in ventilated COVID-19 patients

Plos.org 
En

by Subhadra Mandadi, Harish Pulluru, Frank Annie

Remdesivir (RDV) reduces time to clinical improvement in hospitalized COVID -19 patients requiring supplemental oxygen. Dexamethasone improves survival in those requiring oxygen support. Data is lacking on the efficacy of combination therapy in patients on mechanical ventilation. We analyzed for comparative outcomes between Corticosteroid (CS) therapy with combined Corticosteroid and Remdesivir (CS-RDV) therapy. We conducted an observational... Читать дальше...

LHPE-nets: A lightweight 2D and 3D human pose estimation model with well-structural deep networks and multi-view pose sample simplification method

Plos.org 
En

by Hao Wang, Ming-hui Sun, Hao Zhang, Li-yan Dong

The cross-view 3D human pose estimation model has made significant progress, it better completed the task of human joint positioning and skeleton modeling in 3D through multi-view fusion method. The multi-view 2D pose estimation part of this model is very important, but its training cost is also very high. It uses some deep learning networks to generate heatmaps for each view. Therefore, in this article, we tested some new deep learning networks for pose estimation tasks. Читать дальше...

Pregnancy resumption following contraceptive discontinuation: Hazard survival analysis of the Indonesia Demographic and Health Survey Data 2007, 2012 and 2017

Plos.org 
En

by Maria Gayatri, Budi Utomo, Meiwita Budiharsana, Gouranga Dasvarma

Objective

The objective of this research is to estimate the probability of pregnancy resumption after discontinuing reversible contraceptives—pills, injectables, implants and IUDs, and to examine the factors associated with the resumption of fertility.

Method

The study uses pregnancy calendar data from Indonesia Demographic and Health Surveys (IDHS) of 2007, 2012 and 2017. A hazard model survival method is used... Читать дальше...

Impact of organizational culture, occupational commitment and industry-academy cooperation on vocational education in China: Cross-sectional Hierarchical Linear Modeling analysis

Plos.org 
En

by Yang Lv, Min Wu, Roger C. Shouse

At a time when vocational education is seen as critical for national development, concern grows regarding how weak organizational culture and occupational commitment may threaten the production of quality graduates and teachers within the field. The failure of vocational institutions to effectively create human capital likely threatens the connections between Chinese industry and its educational institutions. This study thus explores how these connections... Читать дальше...

The effect of visual and proprioceptive feedback on sensorimotor rhythms during BCI training

Plos.org 
En

by Hanna-Leena Halme, Lauri Parkkonen

Brain–computer interfaces (BCI) can be designed with several feedback modalities. To promote appropriate brain plasticity in therapeutic applications, the feedback should guide the user to elicit the desired brain activity and preferably be similar to the imagined action. In this study, we employed magnetoencephalography (MEG) to measure neurophysiological changes in healthy subjects performing motor imagery (MI) -based BCI training with two different feedback modalities. Читать дальше...

Correlation analysis of m6A-modified regulators with immune microenvironment infiltrating cells in lung adenocarcinoma

Plos.org 
En

by Wei Ye, Tianpeng Huang

Object

Recent studies have demonstrated the epigenetic regulation of immune responses. However, the potential role of N6-methyladenosine methylation (m6A) in the tumor microenvironment (TME) remains unknown.

Method

In this study, the m6A modification patterns of LUAD samples were comprehensively evaluated by combining TCGA and GEO data, while these modification patterns were systematically linked to the characteristics of immune infiltrating cells in TME. Читать дальше...

Новости России
Москва

«Турбозавры» поучаствовали в Дне московского транспорта


Network pharmacology analysis and molecular docking to unveil the potential mechanisms of San-Huang-Chai-Zhu formula treating cholestasis

Plos.org 
En

by Binbin Liu, Jie Zhang, Lu Shao, Jiaming Yao

Objective

Chinese medicine formulae possess the potential for cholestasis treatment. This study aimed to explore the underlying mechanisms of San-Huang-Chai-Zhu formula (SHCZF) against cholestasis.

Methods

The major chemical compounds of SHCZF were identified by high-performance liquid chromatography. The bioactive compounds and targets of SHCZF, and cholestasis-related targets were obtained from public databases. Intersected targets... Читать дальше...


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