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Новости за 18.03.2022

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The Real Reason We Dread Our Inboxes

The Wall Street Journal 
En

Avoiding difficult questions or uncomfortable interactions is a form of self-sabotage. You can take back control.

HIV-1 infections with multiple founders associate with the development of neutralization breadth

Plos.org 
En

by Eric Lewitus, Samantha M. Townsley, Yifan Li, Gina C. Donofrio, Bethany L. Dearlove, Hongjun Bai, Eric Sanders-Buell, Anne Marie O’Sullivan, Meera Bose, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fredrick K. Sawe, Leigh Anne Eller, Nelson L. Michael, Victoria R. Polonis, Julie A. Ake, Sandhya Vasan, Merlin L. Robb, Sodsai Tovanabutra, Shelly J. Krebs, Morgane Rolland

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The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion

Plos.org 
En

by Shanshan Wang, France Moreau, Kris Chadee

A hallmark of Entamoeba histolytica (Eh) invasion in the gut is acute inflammation dominated by the secretion of pro-inflammatory cytokines TNF-α and IL-1β. This is initiated when Eh in contact with macrophages in the lamina propria activates caspase-1 by recruiting the NLRP3 inflammasome complex in a Gal-lectin and EhCP-A5-dependent manner resulting in the maturation and secretion of IL-1β and IL-18. Here, we interrogated the requirements and... Читать дальше...

Action-driven contrastive representation for reinforcement learning

Plos.org 
En

by Minbeom Kim, Kyeongha Rho, Yong-duk Kim, Kyomin Jung

In reinforcement learning, reward-driven feature learning directly from high-dimensional images faces two challenges: sample-efficiency for solving control tasks and generalization to unseen observations. In prior works, these issues have been addressed through learning representation from pixel inputs. However, their representation faced the limitations of being vulnerable to the high diversity inherent in environments or not taking the characteristics for solving control tasks. Читать дальше...



‘You’re on the waiting list’: An interpretive phenomenological analysis of young adults’ experiences of waiting lists within mental health services in the UK

Plos.org 
En

by Georgia Punton, Alyson L. Dodd, Andrew McNeill

Waiting lists in mental health services are currently considered too long. Lengthy waits of up to 18 weeks are commonly reported in the UK. Waiting lists have long been associated with a variety of negative psychological responses, however there is little understanding behind young adults’ personal experiences of such delays within mental health services. The current study aimed to explore young adults’ experiences of waiting lists in mental healthcare in the UK. Читать дальше...

Advancing the study of solving linear equations with negative pronumerals: A smarter way from a cognitive load perspective

Plos.org 
En

by Bing H. Ngu, Huy P. Phan

Central to cognitive load theory is the concept of element interactivity, which reflects the complexity of material. The complexity of linear equations depends on the number of operational and relational lines and the nature of the operation (balance versus inverse) in the solution procedure. A relational line refers to the quantitative relation whereby the right-hand side of the equation equals to its left-hand side. An operational line refers to the application... Читать дальше...

A secure multi-party computation protocol without CRS supporting multi-bit encryption

Plos.org 
En

by Zong-Wu Zhu, Ru-Wei Huang

To solve the problems in the existing fully homomorphic encryption (FHE)-based secure multi-party computation (SMC) protocols such as low efficiency, the FHE scheme that supports multi-bit encryption was modified during the generation of the public key so that the users could generate their public keys independently without the common random string (CRS) matrix. Further, a multi-bit Gentry-Sahai-Waters scheme (MGSW) scheme without CRS was constructed. The modified... Читать дальше...

Новости России
Москва

Зной идет из Африки. Метеоролог Вильфанд: аномальная жара смертельно опасна


Health status of street children and reasons for being forced to live on the streets in Harar, Eastern Ethiopia. Using mixed methods

Plos.org 
En

by Degu Abate, Addis Eyeberu, Dechasa Adare, Belay Negash, Addisu Alemu, Temam Beshir, Alemayehu Deressa Wayessa, Adera Debella, Nebiyu Bahiru, Helina Heluf, Mohammed Abdurke Kure, Ahmedmenewer Abdu, Amanuel Oljira Dulo, Habtamu Bekele, Kefelegn Bayu, Saron Bogale, Genanaw Atnafe, Tewodros Assefa, Rabuma Belete, Mohammed Muzeyin, Haftu Asmerom, Mesay Arkew, Anumein Mohammed, Henock Asfaw, Barkot Taddesse, Daniel Alemu, Dawit Yihun, Shambel Nigussie, Jemal Yusuf Kebira, Siraj Aliyi Adem, Gebisa Dirirsa... Читать дальше...

Nanoencapsulation of buriti oil (Mauritia flexuosa L.f.) in porcine gelatin enhances the antioxidant potential and improves the effect on the antibiotic activity modulation

Plos.org 
En

by Neyna de Santos Morais, Thaís Souza Passos, Gabriela Rocha Ramos, Victoria Azevedo Freire Ferreira, Susana Margarida Gomes Moreira, Gildácio Pereira Chaves Filho, Ana Paula Gomes Barreto, Pedro Ivo Palacio Leite, Ray Silva de Almeida, Cícera Laura Roque Paulo, Rafael Fernandes, Sebastião Ânderson Dantas da Silva, Sara Sayonara da Cruz Nascimento, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis

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