A pan-cancer analysis on the carcinogenic effect of human adenomatous polyposis coli
by Yinci Zhang, Xinkuang Liu, Amin Li, Xiaolong Tang
Adenomatous polyposis coli (APC) is the most commonly mutated gene in colon cancer and can cause familial adenomatous polyposis (FAP). Hypermethylation of the APC promoter can also promote the development of breast cancer, indicating that APC is not limited to association with colorectal neoplasms. However, no pan-cancer analysis has been conducted. We studied the location and structure of APC and the expression and potential role of APC... Читать дальше...