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2022

Новости за 25.03.2022

National mapping of schistosomiasis, soil-transmitted helminthiasis and anaemia in Yemen: Towards better national control and elimination

Plos.org 

by Nur Alia Johari, Dhekra Amin Annuzaili, Hani Farouk El-Talabawy, Maryam Ba-Break, Abdulsalam M. Al-Mekhlafi, Samira Al-Eryani, Abdulhakim Ali Alkohlani, Albis Francesco Gabrielli, Riadh Ben-Ismail, Sami Alhaidari, Adel Muaydh, Rasheed Alshami, Magid AL Gunaid, Alaa Hamed, Nehad Kamel, Karen Palacio, Fiona Fleming, Michael Duncan French

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SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells

Plos.org 

by Hugo Dorison, Ibtissam Talhaoui, Gerard Mazón

The post-translational modification of DNA damage response proteins with SUMO is an important mechanism to orchestrate a timely and orderly recruitment of repair factors to damage sites. After DNA replication stress and double-strand break formation, a number of repair factors are SUMOylated and interact with other SUMOylated factors, including the Yen1 nuclease. Yen1 plays a critical role in ensuring genome stability and unperturbed chromosome... Читать дальше...



Mining folded proteomes in the era of accurate structure prediction

Plos.org 

by Charles Bayly-Jones, James C. Whisstock

Protein structure fundamentally underpins the function and processes of numerous biological systems. Fold recognition algorithms offer a sensitive and robust tool to detect structural, and thereby functional, similarities between distantly related homologs. In the era of accurate structure prediction owing to advances in machine learning techniques and a wealth of experimentally determined structures, previously curated sequence databases have become a rich source of biological information. Читать дальше...

Review: Bullock, Tatum serve up the charm in ‘The Lost City’

The Toledo Blade 

The Lost City is the kind of charming, star-driven, action-adventure that makes moviemaking look easy and effortless from the outside. It’s hard to imagine a world in which you pair Sandra Bullock and Channing Tatum as a romance novelist and her himbo cover model on a Romancing the Stone-esque journey not being enjoyable. Throw in a bit of Brad Pitt kicking butt without breaking a sweat and a dash of Daniel Radcliffe as an eccentric heir and you’ve got a surefire hit, right?

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