by Beesan Tan, Nicholas Opoku, Simon K. Attah, Kwablah Awadzi, Annette C. Kuesel, Janis Lazdins-Helds, Craig Rayner, Victoria Ryg-Cornejo, Mark Sullivan, Lawrence Fleckenstein
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by Nur Alia Johari, Dhekra Amin Annuzaili, Hani Farouk El-Talabawy, Maryam Ba-Break, Abdulsalam M. Al-Mekhlafi, Samira Al-Eryani, Abdulhakim Ali Alkohlani, Albis Francesco Gabrielli, Riadh Ben-Ismail, Sami Alhaidari, Adel Muaydh, Rasheed Alshami, Magid AL Gunaid, Alaa Hamed, Nehad Kamel, Karen Palacio, Fiona Fleming, Michael Duncan French
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by Zacchaeus Anywaine, Swaib Abubaker Lule, Christian Hansen, George Warimwe, Alison Elliott
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by Karen M. Holcomb, Chilinh Nguyen, Brian D. Foy, Michelle Ahn, Kurt Cramer, Emma T. Lonstrup, Asli Mete, Lisa A. Tell, Christopher M. Barker
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by Lars T. Fadnes, Jan-Magnus Økland, Øystein A. Haaland, Kjell Arne Johansson
by Hugo Dorison, Ibtissam Talhaoui, Gerard Mazón
The post-translational modification of DNA damage response proteins with SUMO is an important mechanism to orchestrate a timely and orderly recruitment of repair factors to damage sites. After DNA replication stress and double-strand break formation, a number of repair factors are SUMOylated and interact with other SUMOylated factors, including the Yen1 nuclease. Yen1 plays a critical role in ensuring genome stability and unperturbed chromosome... Читать дальше...
by Mingyu Song, Yuji K. Takahashi, Amanda C. Burton, Matthew R. Roesch, Geoffrey Schoenbaum, Yael Niv, Angela J. Langdon
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by Charles Bayly-Jones, James C. Whisstock
Protein structure fundamentally underpins the function and processes of numerous biological systems. Fold recognition algorithms offer a sensitive and robust tool to detect structural, and thereby functional, similarities between distantly related homologs. In the era of accurate structure prediction owing to advances in machine learning techniques and a wealth of experimentally determined structures, previously curated sequence databases have become a rich source of biological information. Читать дальше...
by Leonardo Souto Ferreira, Otavio Canton, Rafael Lopes Paixão da Silva, Silas Poloni, Vítor Sudbrack, Marcelo Eduardo Borges, Caroline Franco, Flavia Maria Darcie Marquitti, José Cássio de Moraes, Maria Amélia de Sousa Mascena Veras, Roberto André Kraenkel, Renato Mendes Coutinho
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by Zixin Peng, Alexandre Maciel-Guerra, Michelle Baker, Xibin Zhang, Yue Hu, Wei Wang, Jia Rong, Jing Zhang, Ning Xue, Paul Barrow, David Renney, Dov Stekel, Paul Williams, Longhai Liu, Junshi Chen, Fengqin Li, Tania Dottorini
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by Maxence S. Vincent, Caterina Comas Hervada, Corinne Sebban-Kreuzer, Hugo Le Guenno, Maïalène Chabalier, Artemis Kosta, Françoise Guerlesquin, Tâm Mignot, Mark J. McBride, Eric Cascales, Thierry Doan
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We made it through another week and the only thing we have to show for it is a rise in gas prices, by a whole cent. The national average for a gallon of unleaded regular is $4.24 this morning.
Читать дальше...Nathan Ray Seebeck-USA TODAY Sports
Seems like 2022 is gonna be Ichiro szn.
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Killing Eve’s fierce assassin Villanelle (Jodie Comer) is mending her violent ways in the show’s final season. She was trying to, at least. The fourth season of BBC America’s spy thriller begins with Villanelle leaning on God to absolve her sins. Instead, she’s drawn back into the world of The Twelve, a secret global…
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London is getting a humongous, 21,500-person capacity orb-shaped stadium boasting a “multisensory experience” for its future attendees—presumably most of whom will be there for U2, Coldplay, John Williams soundtrack concerts, and very little else.
Jay Biggerstaff-USA TODAY Sports
A short spring makes for some interesting roster issues, but at least players are performing well enough to bring up the questions.
Читать дальше...The Ibstock actor has shone in both Time and Help
The Lost City is the kind of charming, star-driven, action-adventure that makes moviemaking look easy and effortless from the outside. It’s hard to imagine a world in which you pair Sandra Bullock and Channing Tatum as a romance novelist and her himbo cover model on a Romancing the Stone-esque journey not being enjoyable. Throw in a bit of Brad Pitt kicking butt without breaking a sweat and a dash of Daniel Radcliffe as an eccentric heir and you’ve got a surefire hit, right?
St Louis starts their entry to MLS with a NEXT Pro that already has MLS talent on it. | Photo by David Butow/Corbis via Getty Images
There’s a lot of NorAm soccer to watch this weekend, plus Nouhou.
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In our new podcast interview series, we speak to Zac Barnes of the Riot
Читать дальше...Just weeks after releasing a software for independent medical groups, Verona-based health records giant Epic Systems Corp. is making even more moves that aim to increase healthcare accessibility in the wake of COVID.
(Telecompaper) Beeline Georgia plans to change call rates under its standard tariff plan from 27 April. Calls to all Georgian mobile networks will cost GEL 0.20 per...