Добавить новость
ru24.net
News in English
Календарь
Апрель
2022
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30

Новости за 13.04.2022

151050100271272273274275276277500 >>>

Understanding load in netball – An analysis of multiple seasons, phases, and teams

Plos.org 
En

by Lyndell Bruce, Tanisha Bardzinski, Dan Dwyer

Studies of training and competition load in sport are usually based on data that represents a sample of a league and or annual training program. These studies sometimes explore important factors that are affected by load, such as training adaptations and injury risk. The generalisability of the conclusions of these studies, can depend on how much load varies between seasons, training phases and teams. The interpretation of previous load studies... Читать дальше...



Retinoid-X receptor agonists increase thyroid hormone competence in lower jaw remodeling of pre-metamorphic Xenopus laevis tadpoles

Plos.org 
En

by Brenda J. Mengeling, Lara F. Vetter, J. David Furlow

Thyroid hormone (TH) signaling plays critical roles during vertebrate development, including regulation of skeletal and cartilage growth. TH acts through its receptors (TRs), nuclear hormone receptors (NRs) that heterodimerize with Retinoid-X receptors (RXRs), to regulate gene expression. A defining difference between NR signaling during development compared to in adult tissues, is competence, the ability of the organism to respond to an endocrine signal. Читать дальше...

Morphology of foveal hypoplasia: Hyporeflective zones in the Henle fiber layer of eyes with high-grade foveal hypoplasia

Plos.org 
En

by Andreas Bringmann, Thomas Barth, Focke Ziemssen

Background

Foveal hypoplasia is characterized by the persistance of inner retinal layers at the macular center. We evaluated using spectral-domain optical coherence tomography (SD-OCT) morphological parameters of the macular center of eyes with foveal hypoplasia and describe the presence of hyporeflective zones in the Henle fiber layer (HFL) of eyes with high-grade foveal hypoplasia.

Methods

Eyes with foveal hypoplasia were classified into two groups... Читать дальше...

Device-based measurement of physical activity in pre-schoolers: Comparison of machine learning and cut point methods

Plos.org 
En

by Matthew N. Ahmadi, Stewart G. Trost

Introduction

Machine learning (ML) accelerometer data processing methods have potential to improve the accuracy of device-based assessments of physical activity (PA) in young children. Yet the uptake of ML methods by health researchers has been minimal and the use of cut-points (CP) continues to be the norm, despite evidence of significant misclassification error. The lack of studies demonstrating a relative advantage for ML approaches over CP methods maybe a key contributing factor. Читать дальше...

In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing

Plos.org 
En

by Heather P. McLaughlin, Christopher A. Gulvik, David Sue

Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B. pseudomallei genes encoding putative penicillin binding proteins (PBPs) and investigate their utility for determining phylogeography and differentiating closely related species. We performed in silico analysis to characterize 10 PBP homologs in B. pseudomallei 1026b. Читать дальше...

Новости России

The C-terminal domain of Hsp70 is responsible for paralog-specific regulation of ribonucleotide reductase

Plos.org 
En

by Laura E. Knighton, Nitika, Siddhi Omkar, Andrew W. Truman

The Hsp70 family of molecular chaperones is well-conserved and expressed in all organisms. In budding yeast, cells express four highly similar cytosolic Hsp70s Ssa1, 2, 3 and 4 which arose from gene duplication. Ssa1 and 2 are constitutively expressed while Ssa3 and 4 are induced upon heat shock. Recent evidence suggests that despite their amino acid similarity, these Ssas have unique roles in the cell. Here we examine the relative... Читать дальше...

Filling gaps in bacterial catabolic pathways with computation and high-throughput genetics

Plos.org 
En

by Morgan N. Price, Adam M. Deutschbauer, Adam P. Arkin

To discover novel catabolic enzymes and transporters, we combined high-throughput genetic data from 29 bacteria with an automated tool to find gaps in their catabolic pathways. GapMind for carbon sources automatically annotates the uptake and catabolism of 62 compounds in bacterial and archaeal genomes. For the compounds that are utilized by the 29 bacteria, we systematically examined the gaps in GapMind’s predicted pathways, and we... Читать дальше...


Спорт в России и мире

Новости спорта


Новости тенниса






Спонсорский контент

Все новости smi24.net