Clinician approaches to communicating a dementia diagnosis: An interview study
by Easton N. Wollney, Carma L. Bylund, Noheli Bedenfield, Monica Rosselli, Rosie E. Curiel-Cid, Marcela Kitaigorodsky, Ximena Levy, Melissa J. Armstrong
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by Easton N. Wollney, Carma L. Bylund, Noheli Bedenfield, Monica Rosselli, Rosie E. Curiel-Cid, Marcela Kitaigorodsky, Ximena Levy, Melissa J. Armstrong
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by Rania Soudy, Ryoichi Kimura, Wen Fu, Aarti Patel, Jack Jhamandas
Extracellular vesicles (EVs) are double membrane structures released by all cell types with identified roles in the generation, transportation, and degradation of amyloid-β protein (Aβ) oligomers in Alzheimer’s disease (AD). EVs are thus increasingly recognized to play a neuroprotective role in AD, through their ability to counteract the neurotoxic effects of Aβ, possibly through interactions with specific receptors on cell membranes. Читать дальше...
by Shade T. Shutters, J. M. Applegate
A key driver of urbanization is the pursuit of economic opportunities in cities. One such opportunity is the promise of higher wages in larger cities, a phenomenon known as the urban wage premium. While an urban wage premium has been well-documented among U.S. metropolitan areas, little is known about its existence in micropolitan areas, which represent an important link between rural and dense urban areas. Here we measure the power law scaling coefficient... Читать дальше...
by Noé Patrick M’Bondoukwé, Reinne Moutongo, Komi Gbédandé, Jacques Mari Ndong Ngomo, Tatiana Hountohotegbé, Rafiou Adamou, Jeanne Vanessa Koumba Lengongo, Kowir Pambou Bello, Denise Patricia Mawili-Mboumba, Adrian John Frederick Luty, Marielle Karine Bouyou-Akotet
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by Ariela Mota Ferreira, Laércio Ives Santos, Ester Cerdeira Sabino, Antonio Luiz Pinho Ribeiro, Léa Campos de Oliveira-da Silva, Renata Fiúza Damasceno, Marcos Flávio Silveira Vasconcelos D’Angelo, Maria do Carmo Pereira Nunes, Desirée Sant´Ana Haikal
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by Changli Wang, Lijun Chen, Yaobin Chen, Wenwen Jia, Xunhui Cai, Yufeng Liu, Fenghu Ji, Peng Xiong, Anyi Liang, Ren Liu, Yuanlin Guan, Zhongyi Cheng, Yejing Weng, Weixin Wang, Yaqi Duan, Dong Kuang, Sanpeng Xu, Hanghang Cai, Qin Xia, Dehua Yang, Ming-Wei Wang, Xiangping Yang, Jianjun Zhang, Chao Cheng, Liang Liu, Zhongmin Liu, Ren Liang, Guopin Wang, Zhendong Li, Han Xia, Tian Xia
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by Muriel Desbois, Karla J. Opperman, Jonathan Amezquita, Gabriel Gaglio, Oliver Crawley, Brock Grill
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by Anuradha Kar, Manuel Petit, Yassin Refahi, Guillaume Cerutti, Christophe Godin, Jan Traas
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by Arash Saeidpour, Shweta Bansal, Pejman Rohani
Pertussis has resurfaced in the UK, with incidence levels not seen since the 1980s. While the fundamental causes of this resurgence remain the subject of much conjecture, the study of historical patterns of pathogen diffusion can be illuminating. Here, we examined time series of pertussis incidence in the boroughs of Greater London from 1982 to 2013 to document the spatial epidemiology of this bacterial infection and to identify the potential drivers of its percolation. Читать дальше...
by Carolyn J. Lawrence-Dill, Robyn L. Allscheid, Albert Boaitey, Todd Bauman, Edward S. Buckler IV, Jennifer L. Clarke, Christopher Cullis, Jack Dekkers, Cassandra J. Dorius, Shawn F. Dorius, David Ertl, Matthew Homann, Guiping Hu, Mary Losch, Eric Lyons, Brenda Murdoch, Zahra-Katy Navabi, Somashekhar Punnuri, Fahad Rafiq, James M. Reecy, Patrick S. Schnable, Nicole M. Scott, Moira Sheehan, Xavier Sirault, Margaret Staton, Christopher K. Tuggle, Alison Van Eenennaam, Rachael Voas
by Moustafa Abdalla, Mohamed Abdalla
Genome wide association studies (GWASs) for complex traits have implicated thousands of genetic loci. Most GWAS-nominated variants lie in noncoding regions, complicating the systematic translation of these findings into functional understanding. Here, we leverage convolutional neural networks to assist in this challenge. Our computational framework, peaBrain, models the transcriptional machinery of a tissue as a two-stage process: first, predicting the... Читать дальше...
by James Andrew Smith, Jonas B. Sandbrink
The risk of accidental or deliberate misuse of biological research is increasing as biotechnology advances. As open science becomes widespread, we must consider its impact on those risks and develop solutions that ensure security while facilitating scientific progress. Here, we examine the interaction between open science practices and biosecurity and biosafety to identify risks and opportunities for risk mitigation. Increasing the availability of computational tools... Читать дальше...
Recorded in Birmingham, Alabama, on April 2, 2022.
Special thanks to Mark Walker for sponsoring this event.
Limited to just 1,000 bottles, Distil Your World New York starts at $4,200.
Let's get this straight. Despite the many tips of the hat to Star Trek: Deep Space Nine this season, that. is. not. Bashir.
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The monthly cost of buying a typical home has surged by more than a third over the past year by one estimate, yet demand remains robust.
We’ve seen plenty of twists and turns over the course of Shining Vale‘s first season, and now the Starz series is poised to come to a dramatic end. SheKnows was given an exclusive look at a scene from the last chapter of this installment of the series, and it looks like Rosemary (Mira Sorvino) is finally […]
U.S. oil drillers are pumping more crude as international prices remain elevated amid supply uncertainty and demand strength. Citing industry experts, Reuters reported today that continuing supply chain disruptions and labor shortages are being trumped by optimism about demand, and analysts are revising their U.S. oil output forecasts upward. According to consultancy East Daley Capital, the U.S. will end 2022 with oil production averaging 12.86 million bpd, increasing 1.29 million bpd from 2021. Most of this will come from the Permian Basin... Читать дальше...
Communication is foundational to being an effective leader. Understand the steps to identify and develop an exceptional communication style.
Filed under: Chrysler,Dodge,Jeep,RAM,Emissions,Truck,Coupe,SUV,Performance,Sedan
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Recently, my stepmother made a batch of pepper jelly I can only describe as “violent.” “Yes. I should have warned...
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TGIF right guys? Oh? It’s Thursday? Well... shit.
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As one of the internet’s most meme-friendly file formats, there’s an endless number of tools and websites that can turn short video clips into animated GIFs. When it comes to animating your own doodles and drawings, Arteater makes it as easy as printing a template, expressing yourself creatively, and then uploading a…
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The young actor takes on the classic Barbra Streisand role for the show’s first-ever Broadway revival, which officially opens on April 24.