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TagSeq: Malicious behavior discovery using dynamic analysis

Plos.org 

by Yi-Ting Huang, Yeali S. Sun, Meng Chang Chen

In recent years, studies on malware analysis have noticeably increased in the cybersecurity community. Most recent studies concentrate on malware classification and detection or malicious patterns identification, but as to malware activity, it still relies heavily on manual analysis for high-level semantic descriptions. We develop a sequence-to-sequence (seq2seq) neural network, called TagSeq, to investigate a sequence of Windows API calls recorded from malware execution... Читать дальше...

Laboratory efficacy of selected synthetic insecticides against second instar invasive fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae) larvae

Plos.org 

by Atif Idrees, Ziyad Abdul Qadir, Ayesha Afzal, Qiu Ranran, Jun Li

Maize is the most essential crop of China and its productivity has been recently endangered by the fall armyworm (FAW), Spodoptera frugiperda. Chemical pesticides are one of the most important strategies for managing FAW on a short-term basis. The seven synthetic insecticides including novel and conventional belong to four chemical group, spinetoram and spinosad (spinosyns), lambda-cyhalothrin, cypermethrin and bifenthrin (pyrethroids)... Читать дальше...

A model for isoform-level differential expression analysis using RNA-seq data without pre-specifying isoform structure

Plos.org 

by Yang Liu, Junying Wang, Song Wu, Jie Yang

Motivation

Next generation sequencing (NGS) technology has been widely used in biomedical research, particularly on those genomics-related studies. One of NGS applications is the high-throughput mRNA sequencing (RNA-seq), which is usually applied to evaluate gene expression level (i.e. copies of isoforms), to identify differentially expressed genes, and to discover potential alternative splicing events. Popular tools for differential expression... Читать дальше...

Incidence of tuberculosis among PLHIV on antiretroviral therapy who initiated isoniazid preventive therapy: A multi-center retrospective cohort study

Plos.org 

by Andrew Kazibwe, Bonniface Oryokot, Levicatus Mugenyi, David Kagimu, Abraham Ignatius Oluka, Darlius Kato, Simple Ouma, Edmund Tayebwakushaba, Charles Odoi, Kizito Kakumba, Ronald Opito, Ceasar Godfrey Mafabi, Michael Ochwo, Robert Nkabala, Wilber Tusiimire, Agnes Kateeba Tusiime, Sarah Barbara Alinga, Yunus Miya, Michael Bernard Etukoit, Irene Andia Biraro, Bruce Kirenga

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Validity and reliability of the Polish version of the Self-Compassion Scale and its correlates

Plos.org 

by Dagna Kocur, Maria Flakus, Małgorzata Fopka-Kowalczyk

This study adapts the Self-Compassion Scale into Polish and tests the validity, reliability and factor structure of its measures. In the first phase of the research (Study I), 645 respondents were assessed using the NEO-FFI Scale, the Self-Esteem Scale and a back-translated version of the Self-Compassion Scale. The aim of Study I is to analyse the factor structure of the Polish adaptation of the Self-Compassion Scale. The results of... Читать дальше...

Institutional dynamics and learning networks

Plos.org 

by Philip Poon, Jessica C. Flack, David C. Krakauer

Institutions have been described as ‘the humanly devised constraints that structure political, economic, and social interactions.’ This broad definition of institutions spans social norms, laws, companies, and even scientific theories. We describe a non-equilibrium, multi-scale learning framework supporting institutional quasi-stationarity, periodicity, and switching. Individuals collectively construct ledgers constituting institutions.... Читать дальше...

Tobacco-specific nitrosamine 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA) causes DNA damage and impaired replication/transcription in human lung cells

Plos.org 

by Altaf H. Sarker, Bo Hang

Thirdhand smoke (THS) is a newly described health hazard composed of toxicants, mutagens and carcinogens, including nicotine-derived tobacco specific nitrosamines (TSNAs), one of which is 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA). Although TSNAs are generally potent carcinogens, the risk of NNA, which is specific to THS, is poorly understood. We recently reported that THS exposure-induced adverse impact on DNA replication and transcription with... Читать дальше...

A scenario analysis-based optimal management of water resources supply and demand balance: A case study of Chengdu, China

Plos.org 

by Yang Yu, Tianyu Zhou, Rui Zhao, Zhanglong Li, Chao Shen

Water resources scarcity has threatened the coordinative development of demographics, society and economy. As a typical rapidly urbanizing area and an emerging megacity in China, Chengdu is confronting the pressure of inadequate water supply. The present study divides the macroeconomic factors that affect the water resource supply and demand balance into six major subsystems: water resources supply, water demand, water drainage, population, ecological environment and economy. Читать дальше...

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Москва

Москва прощается с жарой: жителей столицы предупредили о ливнях и грозах


Prevalence and determinants of oral and cervicogenital HPV infection: Baseline analysis of the Michigan HPV and Oropharyngeal Cancer (MHOC) cohort study

Plos.org 

by Andrew F. Brouwer, Lora P. Campredon, Heather M. Walline, Brittany M. Marinelli, Christine M. Goudsmit, Trey B. Thomas, Rachel L. Delinger, Yan Kwan Lau, Emily C. Andrus, Monica L. Yost, Jodi K. McCloskey, Taylor S. Sullivan, Alex S. Mortensen, Suiyuan Huang, Keith Murphy, Bonnie Cheng, Kayla Stanek, Thankam Nair, Thomas E. Carey, Rafael Meza, Marisa C. Eisenberg

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Suillin: A mixed-type acetylcholinesterase inhibitor from Suillus luteus which is used by Saraguros indigenous, southern Ecuador

Plos.org 

by José Miguel Andrade, Pamela Pachar, Luisa Trujillo, Luis Cartuche

Suillus luteus (L.) Roussel is an edible mushroom commonly known as slippery jack or “Kallampa” by indigenous people from Loja province. It is used in traditional medicine to manage gastrointestinal disorders and headaches. In addition, edible mushrooms have been used for neurodegenerative diseases; however, there is no report about the anticholinesterase effect produced by this species. The aim of this work was to isolate... Читать дальше...

Health disparities and COVID-19: A retrospective study examining individual and community factors causing disproportionate COVID-19 outcomes in Cook County, Illinois

Plos.org 

by Larissa H. Unruh, Sadhana Dharmapuri, Yinglin Xia, Kenneth Soyemi

Early data from the COVID-19 pandemic suggests that the disease has had a disproportionate impact on communities of color with higher infection and mortality rates within those communities. This study used demographic data from the 2018 US census estimates, mortality data from the Cook County Medical Examiner’s office, and testing results from the Illinois Department of Public Health to perform bivariate and multivariate... Читать дальше...


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