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Новости за 19.08.2022

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses

Plos.org 

by Pierre Barrat-Charlaix, Timothy G. Vaughan, Richard A. Neher

When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been involved in the emergence of most pandemic influenza strains. However, because of the difficulty in identifying reassortments events from viral sequence data, little is known about its role in the evolution of the seasonal influenza viruses. Читать дальше...

Modeling age-specific incidence of colon cancer via niche competition

Plos.org 

by Steffen Lange, Richard Mogwitz, Denis Hünniger, Anja Voß-Böhme

Cancer development is a multistep process often starting with a single cell in which a number of epigenetic and genetic alterations have accumulated thus transforming it into a tumor cell. The progeny of such a single benign tumor cell expands in the tissue and can at some point progress to malignant tumor cells until a detectable tumor is formed. The dynamics from the early phase of a single cell to a detectable tumor with... Читать дальше...

Mitochondrial mRNA localization is governed by translation kinetics and spatial transport

Plos.org 

by Ximena G. Arceo, Elena F. Koslover, Brian M. Zid, Aidan I. Brown

For many nuclear-encoded mitochondrial genes, mRNA localizes to the mitochondrial surface co-translationally, aided by the association of a mitochondrial targeting sequence (MTS) on the nascent peptide with the mitochondrial import complex. For a subset of these co-translationally localized mRNAs, their localization is dependent on the metabolic state of the cell, while others are constitutively localized. To explore the... Читать дальше...



Recombination-aware phylogeographic inference using the structured coalescent with ancestral recombination

Plos.org 

by Fangfang Guo, Ignazio Carbone, David A. Rasmussen

Movement of individuals between populations or demes is often restricted, especially between geographically isolated populations. The structured coalescent provides an elegant theoretical framework for describing how movement between populations shapes the genealogical history of sampled individuals and thereby structures genetic variation within and between populations. However, in the presence of recombination an individual may inherit... Читать дальше...

Avoiding costly mistakes in groups: The evolution of error management in collective decision making

Plos.org 

by Alan Novaes Tump, Max Wolf, Pawel Romanczuk, Ralf H. J. M. Kurvers

Individuals continuously have to balance the error costs of alternative decisions. A wealth of research has studied how single individuals navigate this, showing that individuals develop response biases to avoid the more costly error. We, however, know little about the dynamics in groups facing asymmetrical error costs and when social influence amplifies either safe or risky behavior. Here, we investigate this by modeling... Читать дальше...

Combined methods reveal task activation dynamics in human brain networks

Plos.org 

by Zach Ladwig, Yuhua Yu, Caterina Gratton

A clear understanding of how human brain networks reflect task performance has been lacking, in part due to methodological difficulties. A new study combines the temporal resolution of EEG, MRI source localization, and multivariate modeling to address this need. This Primer explores a new study in PLOS Biology that combines the millisecond temporal resolution of EEG with MRI-based source localization and multivariate modeling to track dynamic task... Читать дальше...

Designing and implementing a research integrity promotion plan: Recommendations for research funders

Plos.org 

by Serge P. J. M. Horbach, Lex M. Bouter, George Gaskell, Maura Hiney, Panagiotis Kavouras, Niels Mejlgaard, Nick Allum, Noémie Aubert Bonn, Anna-Kathrine Bendtsen, Costas A. Charitidis, Nik Claesen, Kris Dierickx, Anna Domaradzka, Andrea Reyes Elizondo, Nicole Föger, Wolfgang Kaltenbrunner, Teodora Konach, Krishma Labib, Ana Marušić, Daniel Pizzolato, Tine Ravn, Rea Roje, Mads P. Sørensen, Borana Taraj, Giuseppe A. Veltri, Joeri K. Tijdink

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Новости России
Москва

Врач-офтальмолог Элина Санторо: как выбрать идеальные солнцезащитные очки


Shell Slashes Refinery Output In EU As Drought Disrupts Transportation

Oilprice.com 

Shell slashed its refinery output at its Shell Energy and Chemicals Park Rheinland fuel-making facility as low Rhine River levels halted the flow of goods, Shell said on Thursday. "Due to the low Rhine water level we have reduced the capacity of Shell Energy and Chemicals Park Rhineland. The situation regarding supply is challenging but carefully managed," Shell said in an emailed statement to Reuters. In November, Shell announced its plan to shift the refinery in Wesseling in Germany away from crude... Читать дальше...


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