by Azumi Ishizaki, Xiuqiong Bi, Quynh Thi Nguyen, Tomomi Maeno, Akinori Hara, Hiroyuki Nakamura, Sanae Kuramoto, Koichi Nishi, Hiroyasu Ooe, Hiroshi Ichimura
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by Prateep Duengkae, Nattakan Ariyaraphong, Wanlaya Tipkantha, Waleemas Jairak, Sudarath Baicharoen, Dung Ho My Nguyen, Onjira Korboon, Worapong Singchat, Thitipong Panthum, Syed Farhan Ahmad, Erngsiri Kaewkhunjob, Chavin Chaisonkhram, Umaporn Maikaew, Narongrit Muangmai, Gittiyaporn Ieamsaard, Supaphen Sripiboon, Paanwaris Paansri, Warong Suksavate, Aingorn Chaiyes, Supagit Winitpornsawan, Umphornpimon Prayoon, Thiti Sornsa, Ratchanee Chokcharoen, Annop Buanual, Boripat Siriaroonrat, Yongchai Utara... Читать дальше...
by Omid Nasiri, Mahsa Hajihassani, Narjes Noori Goodarzi, Sepideh Fereshteh, Negin Bolourchi, Farzaneh Firoozeh, Omid Azizi, Farzad Badmasti
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by Fang Liu, Alice Y. M. Jones, Raymond C. C. Tsang, Fubing Zha, Mingchao Zhou, Kaiwen Xue, Zeyu Zhang, Yulong Wang
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by Jourdan K. P. McMillan, Patrick O’Donnell, Sandra P. Chang
B cells represent a critical component of the adaptive immune response whose development and differentiation are determined by antigen-dependent and antigen-independent interactions. In this study, we explored the effects of IL-4 and pattern-recognition receptor (PRR) ligands on B cell development and differentiation by investigating their capacity to drive the in vitro maturation of human transitional B cells. In the presence of IL-4... Читать дальше...
by Simon Rahn, Marion Gödel, Gerta Köster, Gesine Hofinger
The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has been identified as essential for transmission. This information is crucial to slow the spread, but the individual likelihood of becoming infected in everyday situations remains uncertain. Mathematical models help estimate such risks. Читать дальше...
by Maria Isabel Garcia-Rojas, Marie R. Keatley, Nadiah Roslan
In the absence of historical information on phenology available in Australia, expert opinion was used for selecting indicator species that would be suitable for monitoring phenology on a continental scale as part of ClimateWatch—a citizen science program. Jacaranda mimosifolia being the most frequently observed species was used in this study to test expert opinion and the adequacy of citizen science records in detecting the influence... Читать дальше...
by Jaeeun Yoo, Hyung Suk Cho, Jae-Ho Yoon, Byung Sik Cho, Hee-Je Kim, Dong-Gun Lee, Dong Wook Jekarl, Myungshin Kim, Eun-Jee Oh, Yeon-Joon Park, Yonggoo Kim
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by Fangyu Shi, Xia Qiu, Mingjing Yu, Yan Huang
ObjectiveTuberculous meningitis (TBM) is one of the most devastating TB. Accurate identification of TBM is helpful to eliminate TB. Therefore, we assessed the performance of TBAg stimulated IFN-γ (IGRA) and unstimulated IFN-γ in blood and cerebrospinal fluid (CSF) for diagnosing TBM.
MethodsWe searched Web of Science, PubMed, Embase and the Cochrane Library databases until March 2022. Bivariate and hierarchical summary receiver operating... Читать дальше...
by Kathryn E. Seeley, Kathryn L. Proudfoot, Ashley N. Edes
Principles of allostasis and allostatic load have been widely applied in human research to assess the impacts of chronic stress on physiological dysregulation. Over the last few decades, researchers have also applied these concepts to non-human animals. However, there is a lack of uniformity in how the concept of allostasis is described and assessed in animals. The objectives of this review were to: 1) describe the extent to which... Читать дальше...
by Hasanur Bin Khazri, Sadia Choudhury Shimmi, M. Tanveer Hossain Parash
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by Gyung Deok Han, Jeong Min Choi, Inchan Choi, Yoonha Kim, Seong Heo, Yong Suk Chung
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by Li Luyao, Abdullah Al Mamun, Naeem Hayat, Qing Yang, Mohammad Enamul Hoque, Noor Raihani Zainol
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by Pascale Plaisancié, Charline Buisson, Edwin Fouché, Pierre Martin, Céline Noirot, Claire Maslo, Jacques Dupuy, Françoise Guéraud, Fabrice Pierre
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by Rebecca A. Cox, Scott A. Read, Shelley Hopkins, David Alonso-Caneiro, Joanne M. Wood
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by Jason Richwine
Researchers have long observed that foreign-educated immigrants earn lower wages and hold less-skilled jobs than U.S. natives who have the same level of educational attainment, but the reasons for the disparity have been less clear. This paper tests the hypothesis favored by the human capital model of earnings and employment–namely, that foreign-educated immigrants struggle in the U.S. labor market primarily because they possess fewer marketable skills than workers with... Читать дальше...
by Antonella Santona, Najwa A. Mhmoud, Emmanuel Edwar Siddig, Massimo Deligios, Maura Fiamma, Bianca Paglietti, Sahar Mubarak Bakhiet, Salvatore Rubino, Ahmed Hassan Fahal
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by Michael Marks, Jodie McVernon, James S. McCarthy, Wendemagegn Enbiale, Christopher Hanna, Olivier Chosidow, Daniel Engelman, Kingsley Asiedu, Andrew Steer
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by Raman Mahajan, Sophie I. Owen, Shiril Kumar, Krishna Pandey, Shahwar Kazmi, Vikash Kumar, Emily R. Adams, Amit Harshana, Sakib Burza
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by Chibuike Ibe
Invasive fungal infections (IFIs) have been described as diseases of the poor. The mortality rate of the infections is comparable to that of malaria, HIV, and TB, yet the infections remain poorly funded, neglected in research, and policy at all levels of human resources. The Coronavirus Disease 2019 (COVID-19) pandemic has further worsened the current state of management for IFIs. At the same time, response to COVID-19 has stirred and boosted vaccine production, vaccine substance manufacturing... Читать дальше...
by Habtye Bisetegn, Daniel Getacher Feleke, Habtu Debash, Yonas Erkihun, Hussen Ebrahim
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by Tashrik Ahmed, Timothy Roberton, Petra Vergeer, Peter M. Hansen, Michael A. Peters, Anthony Adofo Ofosu, Charles Mwansambo, Charles Nzelu, Chea Sanford Wesseh, Francis Smart, Jean Patrick Alfred, Mamoutou Diabate, Martina Baye, Mohamed Lamine Yansane, Naod Wendrad, Nur Ali Mohamud, Paul Mbaka, Sylvain Yuma, Youssoupha Ndiaye, Husnia Sadat, Helal Uddin, Helen Kiarie, Raharison Tsihory, George Mwinnyaa, Jean de Dieu Rusatira, Pablo Amor Fernandez, Pierre Muhoza, Prativa Baral, Salomé Drouard... Читать дальше...
by Thomas Brazier, Sylvain Glémin
During meiosis, crossover rates are not randomly distributed along the chromosome and their location may have a strong impact on the functioning and evolution of the genome. To date, the broad diversity of recombination landscapes among plants has rarely been investigated and a formal comparative genomic approach is still needed to characterize and assess the determinants of recombination landscapes among species and chromosomes. We gathered genetic maps and genomes for 57 flowering plant species... Читать дальше...
by Yosuke Tanigawa, Ethan S. Dyer, Gill Bejerano
We present WhichTF, a computational method to identify functionally important transcription factors (TFs) from chromatin accessibility measurements. To rank TFs, WhichTF applies an ontology-guided functional approach to compute novel enrichment by integrating accessibility measurements, high-confidence pre-computed conservation-aware TF binding sites, and putative gene-regulatory models. Comparison with prior sheer abundance-based methods reveals... Читать дальше...
by Melanie H. Chitwood, Marcus Russi, Kenneth Gunasekera, Joshua Havumaki, Fayette Klaassen, Virginia E. Pitzer, Joshua A. Salomon, Nicole A. Swartwood, Joshua L. Warren, Daniel M. Weinberger, Ted Cohen, Nicolas A. Menzies
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