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Новости за 12.01.2023

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Signature selection forces and evolutionary divergence of immune-survival genes compared between two important shrimp species

Plos.org 
En

by Tze Chiew Christie Soo, Subha Bhassu

In recent years, shrimp aquaculture industry had grown significantly to become the major source of global shrimp production. Despite that, shrimp aquaculture production was impeded by various shrimp diseases over the past decades. Interestingly, different shrimp species demonstrated variable levels of immune strength and survival (immune-survival) ability towards different diseases, especially the much stronger immune-survival ability shown by the ancient shrimp species... Читать дальше...

Factors influencing the use of therapeutic footwear in persons with diabetes mellitus and loss of protective sensation: A focus group study

Plos.org 
En

by Athra Malki, Gijsbertus J. Verkerke, Rienk Dekker, Juha M. Hijmans

Background

Persons with diabetes mellitus (DM) and loss of protective sensation (LOPS) due to peripheral neuropathy do not use their therapeutic footwear (TF) consistently. TF is essential to prevent foot ulceration. In order to improve compliance in using TF, influencing factors need to be identified and analyzed. Persons with a history of foot ulceration may find different factors important compared with persons without... Читать дальше...

Refractive changes after strabismus surgery in patients with intermittent exotropia

Plos.org 
En

by Yeji Moon, Seong-Joon Kim

Objectives

To evaluate the long-term refractive changes after horizontal muscle surgery in patients with intermittent exotropia and investigate the correlation between changes in the postoperative refractive error and clinical factors.

Methods

We retrospectively reviewed the clinical data of patients aged < 15 years who underwent unilateral strabismus surgery (lateral rectus recession and medial rectus resection [RR, n = 47], lateral rectus recession and medial rectus plication [RP... Читать дальше...



Difficulties in summing log-normal distributions for abundance and potential solutions

Plos.org 
En

by Emma J. Talis, Christian Che-Castaldo, Heather J. Lynch

The log-normal distribution, often used to model animal abundance and its uncertainty, is central to ecological modeling and conservation but its statistical properties are less intuitive than those of the normal distribution. The right skew of the log-normal distribution can be considerable for highly uncertain estimates and the median is often chosen as a point estimate. However, the use of the median can become complicated when... Читать дальше...

The United States Food and Drug Administration (FDA) regulatory response to combat neglected tropical diseases (NTDs): A review

Plos.org 
En

by Sanjana Mukherjee

The availability and accessibility of safe and effective drugs, vaccines, and diagnostics are essential to reducing the immense global burden of neglected tropical diseases (NTDs). National regulatory authorities, such as the United States Food and Drug Administration (FDA), play an essential role in this effort to ensure access to safe and effective medical products by working within a set of legal frameworks and regulatory functions. However, medical product development for NTDs remains neglected... Читать дальше...

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Москва

QR-платежи: от простого к сложному — полный гид по современным способам оплаты


Individual variation in Plasmodium vivax malaria risk: Are repeatedly infected people just unlucky?

Plos.org 
En

by Rodrigo M. Corder, Ana Paula Arez, Marcelo U. Ferreira

Extensive research has examined why some people have frequent Plasmodium falciparum malaria episodes in sub-Saharan Africa while others remain free of disease most of the time. In contrast, malaria risk heterogeneity remains little studied in regions where P. vivax is the dominant species. Are repeatedly infected people in vivax malaria settings such as the Amazon just unlucky? Here, we briefly review evidence that human genetic polymorphism... Читать дальше...

A unitary model of auditory frequency change perception

Plos.org 
En

by Kai Siedenburg, Jackson Graves, Daniel Pressnitzer

Changes in the frequency content of sounds over time are arguably the most basic form of information about the behavior of sound-emitting objects. In perceptual studies, such changes have mostly been investigated separately, as aspects of either pitch or timbre. Here, we propose a unitary account of “up” and “down” subjective judgments of frequency change, based on a model combining auditory correlates of acoustic cues in a sound-specific and listener-specific manner. Читать дальше...


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