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Новости за 19.04.2023

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A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

Plos.org 
En

by Megan A. O’Connor, David W. Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B. Lewis, Brieann Brown, Megan N. Fredericks, Kaitlin R. Sprouse, Hillary C. Tunggal, Mara Maughan, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A. Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, David Veesler, Paul T. Edlefsen, Amit P. Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H. Erasmus

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Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

Plos.org 
En

by Rachele M. Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W. Morrow, Alexandra M. Ortiz, Christine M. Fennessey, Miranda B. Fischer, Oriene Shiel, Tonya Swanson, Christine M. Shriver-Munsch, Hugh B. Crank, Kimberly M. Armantrout, Aaron M. Barber-Axthelm, Charlotte Langner, Cassandra R. Moats, Caralyn S. Labriola, Rhonda MacAllister, Michael K. Axthelm, Jason M. Brenchley, Brandon F. Keele, Jacob D. Estes, Scott G. Hansen, Jeremy V. Smedley

The impact of physical environments on outpatient mental health recovery: A design-oriented qualitative study of patient perspectives

Plos.org 
En

by Tiffany Y. Sui, Shannon McDermott, Brooke Harris, Honor Hsin

The physical environment has been shown to affect the emotional states of patients receiving mental health treatment, yet it remains unknown whether physical space design may play a role in optimizing the delivery of mental health care. Principles of architectural design and human-centered co-design have been applied to enhance the patient experience of facility environments; however, little is known about how patients view the impact of physical spaces on their recovery. Читать дальше...



Efficacy and safety of intravenous glucocorticoid therapy for IgG4-related ophthalmic disease

Plos.org 
En

by Min Kyu Yang, Gye Jung Kim, Yeong A. Choi, Ho-Seok Sa

Purpose

To evaluate and compare the efficacy and safety of intravenous (IV) glucocorticoid therapy with those of oral glucocorticoids as a first-line treatment for IgG4-related ophthalmic disease (IgG4-ROD).

Methods

We retrospectively reviewed the medical records of patients who underwent systemic glucocorticoid therapy for biopsy-proven IgG4-ROD from June 2012 to June 2022. Glucocorticoids were given either oral prednisolone... Читать дальше...

Новости России
Москва

«Турбозавры» поучаствовали в Дне московского транспорта


Hippocampal 4-Hz oscillations emerge during stationary running in a wheel and are resistant to medial septum inactivation

Plos.org 
En

by Ivan Alisson Cavalcante Nunes de Lima, Hindiael Belchior

Recent studies described 2–4 Hz oscillations in the hippocampus of rats performing stationary locomotion on treadmills and other apparatus. Since the 2–4 Hz rhythm shares common features with theta (5–12 Hz) oscillations—such as a positive amplitude-running speed relationship and modulation of spiking activity—many have questioned whether these rhythms are related or independently generated. Here, we analyzed local field potentials... Читать дальше...


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Уимблдон

«Гордимся!»: Рустам Минниханов отметил успех Вероники Кудерметовой на Уимблдоне






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