Racial differences in quantitative optical coherence tomography angiography findings between older non-diabetics with co-morbidities
by John Moir, Sarah H. Rodriguez, Lindsay Y. Chun, Nathalie Massamba, Dimitra Skondra
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by John Moir, Sarah H. Rodriguez, Lindsay Y. Chun, Nathalie Massamba, Dimitra Skondra
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by Naoki Takegawa, Taku Hirabayashi, Shunta Tanaka, Michiko Nishikawa, Nagahiro Tokuyama, Takuya Mimura, Saeko Kushida, Hidetaka Tsumura, Yoshinobu Yamamoto, Ikuya Miki, Masahiro Tsuda
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by Joshua Aaron Miller, Libuše Hannah Vepřek, Sebastian Deterding, Seth Cooper
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by Lamia Al Saikhan
BackgroundEvidence related to work-related musculoskeletal pain (WRMSP) among cardiac sonographers is incomplete. This study aimed to investigate the prevalence, characteristics, consequences, and awareness of WRMSP among cardiac sonographers compared with other healthcare workers in different healthcare settings in Saudi Arabia.
MethodsThis was a descriptive, cross-sectional, survey-based study. An electronic self-administered survey using a modified version... Читать дальше...
by Danilo de Iure, Allegra Conti, Angelo Galante, Sara Spadone, Ingo Hilschenz, Massimo Caulo, Stefano Sensi, Cosimo Del Gratta, Stefania Della Penna
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by Sarah Hunt, Jenna Simpson, Lyndon Letwin, Bryan MacLeod
IntroductionThe COVID-19 pandemic necessitated a shift to virtual curriculum delivery at Canadian medical schools. At the NOSM University, some learners transitioned to entirely online learning, while others continued in-person, in-clinic learning. This study aimed to show that medical learners who transitioned to exclusively online learning exhibited higher levels of burnout compared to their peers who continued in-person, clinical learning. Читать дальше...
by Mei Sugawara-Suda, Keitaro Morishita, Osamu Ichii, Takashi Namba, Keisuke Aoshima, Yumiko Kagawa, Sangho Kim, Kenji Hosoya, Nozomu Yokoyama, Noboru Sasaki, Kensuke Nakamura, Jumpei Yamazaki, Mitsuyoshi Takiguchi
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by Young-ho Jung, Hyuk Jin Choi, Mee Kum Kim, Joo Youn Oh
PurposeTo investigate the causes of bullous keratopathy (BK) in the Korean population and analyze the results of penetrating keratoplasty (PK) in BK eyes associated with the top two causes: pseudophakic bullous keratopathy (PBK) and glaucoma surgery-associated BK (GBK).
MethodsMedical records were reviewed of patients diagnosed with BK at a tertiary referral center between 2010 and 2020. The predisposing conditions, clinical... Читать дальше...
by Ettore Epifania, Alessandro E. di Lauro, Pietro Ausiello, Alessia Mancone, Franklin Garcia-Godoy, João Paulo Mendes Tribst
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by Sireen M. Alkhaldi, Oqba Al-Kuran, Mai M. AlAdwan, Tala A. Dabbah, Heyam F. Dalky, Eiman Badran
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by Yoshino Tsurusaki, Yuki Watanabe, Rika Numano, Takayuki Shibata, Hirofumi Kurita
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by Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto
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by Namita Varudkar, Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja Copik, Griffith D. Parks
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by Kedong Wu, Tianshan Yang, Mengchun Zhu
Innovation efficiency is an important manifestation of regional innovation capacity, and how to improve regional innovation efficiency is crucial to regional development. This study empirically explores the impact of industrial intelligence on regional innovation efficiency and the possible influence of approaches and mechanisms. The empirical results revealed the following. First, the development level of industrial intelligence can positively affect regional innovation efficiency... Читать дальше...
by Samia Alamrani, Adrian Gardner, Deborah Falla, Emily Russell, Alison B. Rushton, Nicola R. Heneghan
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by José Ventura-León, Cristopher Lino-Cruz
In recent years, couples have been affected by health measures related to COVID-19, a circumstance that forces us to examine couple interactions in terms of crucial variables of their functioning. In this sense, the present study aimed to examine the association between love, jealousy, satisfaction, and violence in young couples through network analysis. A total of 834 young people and adults between 18 and 38 years of age (Mean = 20.97, SD = 2.39)... Читать дальше...
by Casey Gonzales, Yuejin Liang, James Fisher, Galen Card, Jiaren Sun, Lynn Soong
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by The PLOS Negelected Tropical Diseases Staff
by Khoi Huynh, Brittny R. Smith, Stuart J. Macdonald, Anthony D. Long
We use ATAC-seq to examine chromatin accessibility for four different tissues in Drosophila melanogaster: adult female brain, ovaries, and both wing and eye-antennal imaginal discs from males. Each tissue is assayed in eight different inbred strain genetic backgrounds, seven associated with a reference quality genome assembly. We develop a method for the quantile normalization of ATAC-seq fragments and test for differences in coverage among genotypes... Читать дальше...
by Frances Caroline Lowder, Lyle A. Simmons
The current model for Okazaki fragment maturation in bacteria invokes RNA cleavage by RNase H, followed by strand displacement synthesis and 5′ RNA flap removal by DNA polymerase I (Pol I). RNA removal by Pol I is thought to occur through the 5′-3′ flap endo/exonuclease (FEN) domain, located in the N-terminus of the protein. In addition to Pol I, many bacteria encode a second, Pol I-independent FEN. The contribution of Pol I and Pol I-independent... Читать дальше...
by Briana Wilson, Zhangli Su, Pankaj Kumar, Anindya Dutta
MicroRNAs (miRNAs) are a well-characterized class of small RNAs (sRNAs) that regulate gene expression post-transcriptionally. miRNAs function within a complex milieu of other sRNAs of similar size and abundance, with the best characterized being tRNA fragments or tRFs. The mechanism by which the RNA-induced silencing complex (RISC) selects for specific sRNAs over others is not entirely understood in human cells. Several highly expressed... Читать дальше...
by Alan Min, Timothy Durham, Louis Gevirtzman, William Stafford Noble
Single cell ATAC-seq (scATAC-seq) enables the mapping of regulatory elements in fine-grained cell types. Despite this advance, analysis of the resulting data is challenging, and large scale scATAC-seq data are difficult to obtain and expensive to generate. This motivates a method to leverage information from previously generated large scale scATAC-seq or scRNA-seq data to guide our analysis of new scATAC-seq datasets. We... Читать дальше...
by Megan M. Sperry, Tomiko T. Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K. Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E. Carlson, Ronald J. Wong, Idit Kosti, Brian L. Le, James Logue, Holly Hammond, Matthew Frieman, David K. Stevenson, Donald E. Ingber, Marina Sirota, Richard Novak
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by Jacob R. Pennington, Stephen V. David
Convolutional neural networks (CNNs) can provide powerful and flexible models of neural sensory processing. However, the utility of CNNs in studying the auditory system has been limited by their requirement for large datasets and the complex response properties of single auditory neurons. To address these limitations, we developed a population encoding model: a CNN that simultaneously predicts activity of several hundred neurons recorded during presentation of a large set of natural sounds. Читать дальше...
by Tianhe Wang, Yingrui Luo, Richard B. Ivry, Jonathan S. Tsay, Ernst Pöppel, Yan Bao
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