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Новости за 22.08.2023

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Factors related to subjective well-being among community-dwelling older adults living alone: A stratified analysis by sex and marital status from the JAGES

Plos.org 
En

by Nana Abe, Nanami Oe, Etsuko Tadaka, Toshiyuki Ojima

Background

Previous cross-sectional studies suggest that negative health outcomes such as mortality, social isolation, loneliness, and depression among older adults living alone vary by sex and marital status, with men often worse off than women and unmarried people worse off than married people. However, limited evidence exists from longitudinal studies regarding whether positive health outcomes such as subjective well-being (SWB) also vary by sex and marital status. Читать дальше...

A randomised controlled trial of email versus mailed invitation letter in a national longitudinal survey of physicians

Plos.org 
En

by Benjamin Harrap, Tamara Taylor, Grant Russell, Anthony Scott

Despite their low cost, the use of email invitations to distribute surveys to medical practitioners have been associated with lower response rates. This research compares the difference in response rates from using email approach plus online completion rather than a mailed invitation letter plus a choice of online or paper completion. A parallel randomised controlled trial was conducted during the 11th annual wave of the nationally representative Medicine in Australia... Читать дальше...



Structural bioinformatics studies of bacterial outer membrane beta-barrel transporters and their AlphaFold2 predicted water-soluble QTY variants

Plos.org 
En

by Akash Sajeev-Sheeja, Eva Smorodina, Shuguang Zhang

Beta-barrel outer membrane proteins (OMP) are integral components of Gram-negative bacteria, eukaryotic mitochondria, and chloroplasts. They play essential roles in various cellular processes including nutrient transport, membrane stability, host-pathogen interactions, antibiotic resistance and more. The advent of AlphaFold2 for accurate protein structure predictions transformed structural bioinformatic studies. We previously used a QTY... Читать дальше...

Management goals of type 1 Gaucher disease in South Africa: An expert Delphi consensus document on good clinical practice

Plos.org 
En

by Vernon Johan Louw, Ilanca Fraser, Pilar Giraldo

Background

Gaucher disease is a rare autosomal recessive glycosphingolipid storage disease that ultimately leads to reduced life expectancy. Management of Gaucher disease is challenging due to its wide genotypic and phenotypic variability and changing clinical manifestations due to effective treatment. Deliberation between experts is essential to discuss daily clinical practice and identify controversies regarding the management of Gaucher disease. Читать дальше...

Ways into physical (in)activity: The role of critical life events and transitions in the reconstructions of young adults

Plos.org 
En

by Hannes Gropper, Jannika M. John, Ansgar Thiel

Background

Physical activity (PA), sport, and exercise levels generally tend to fluctuate or decline from childhood to adulthood. Life events and transitions may have a positive or negative impact on these behaviors. However, most research in this regard is quantitatively framed and we know little about why and how life events and transitions affect PA-related behaviors.

Objectives

The aim of this study is to understand when, why, and how individuals change their daily PA... Читать дальше...

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Cumulative multisensory discrepancies shape the ventriloquism aftereffect but not the ventriloquism bias

Plos.org 
En

by Christoph Kayser, Hame Park, Herbert Heuer

Multisensory integration and recalibration are two processes by which perception deals with discrepant signals. Both are often studied in the spatial ventriloquism paradigm. There, integration is probed by the presentation of discrepant audio-visual stimuli, while recalibration manifests as an aftereffect in subsequent judgements of unisensory sounds. Both biases are typically quantified against the degree of audio-visual discrepancy, reflecting... Читать дальше...

The experiences of medical students with ADHD: A phenomenological study

Plos.org 
En

by Megan Godfrey-Harris, Sebastian Charles Keith Shaw

Attention Deficit/Hyperactivity ‘Disorder’ (ADHD) is a form of neurodivergence, characterised by lifelong differences in attention, impulsivity, and hyperactivity. University students with ADHD underachieve academically and tend to have lower levels of self-esteem. Medical schools have an obligation to minimise barriers for students with ADHD. Understanding the experiences of medical students with ADHD is vital to promote inclusive approaches. Читать дальше...


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