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Новости за 23.02.2024

A simulation framework to determine optimal strength training and musculoskeletal geometry for sprinting and distance running

Plos.org 

by Tom Van Wouwe, Jennifer Hicks, Scott Delp, Karen C. Liu

Musculoskeletal geometry and muscle volumes vary widely in the population and are intricately linked to the performance of tasks ranging from walking and running to jumping and sprinting. As an alternative to experimental approaches, where it is difficult to isolate factors and establish causal relationships, simulations can be used to independently vary musculoskeletal geometry and muscle volumes, and develop a fundamental understanding. Читать дальше...

Shared input and recurrency in neural networks for metabolically efficient information transmission

Plos.org 

by Tomas Barta, Lubomir Kostal

Shared input to a population of neurons induces noise correlations, which can decrease the information carried by a population activity. Inhibitory feedback in recurrent neural networks can reduce the noise correlations and thus increase the information carried by the population activity. However, the activity of inhibitory neurons is costly. This inhibitory feedback decreases the gain of the population. Thus, depolarization of its neurons requires stronger excitatory synaptic input... Читать дальше...



Sublethal thermal stress promotes migration and invasion of thyroid cancer cells

Plos.org 

by Chi-Yu Kuo, Chung-Hsin Tsai, Jun Kui Wu, Shih-Ping Cheng

Objective

Radiofrequency ablation is a viable option in the treatment of benign thyroid nodules. Some reports suggest that thermal ablation may also be safe for the management of low-risk thyroid cancer. In this study, we applied transient heat treatment to thyroid cancer cells to mimic clinical scenarios in which insufficient ablation leads to incomplete eradication of thyroid cancer.

Methods

Differentiated thyroid cancer cell lines B-CPAP... Читать дальше...

A triangular model of fractal growth with application to adsorptive spin-coating of polymers

Plos.org 

by Kenneth Mulder, Sophia M. Lee, Wei Chen

Over the last 40 years, applied mathematicians and physicists have proposed a number of mathematical models that produce structures exhibiting a fractal dimension. This work has coincided with the discovery that objects with fractal dimension are relatively common in the natural and human-produced worlds. One particularly successful model of fractal growth is the diffusion limited aggregation (DLA) model, a model as notable for its simplicity as for its complex and varied behavior. Читать дальше...

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