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2024

Новости за 09.04.2024

Spatial characteristics of non-communicable diseases and their associations to social conditions in a large urban cohort in Germany—Results from the Hamburg City Health Study

Plos.org 

by Valerie Andrees, Ramona Bei der Kellen, Matthias Augustin, Jürgen Gallinat, Volker Harth, Hanno Hoven, Simone Kühn, Anne Lautenbach, Christina Magnussen, Nicole Mohr, Raphael Twerenbold, Ines Schäfer, Benjamin Waschki, Birgit-Christiane Zyriax, Jobst Augustin

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Risk relationship between inflammatory bowel disease and urolithiasis: A two-sample Mendelian randomization study

Plos.org 

by Wenqiang Fu, Bin Zhu, Jun Chen, Xuelin Jin

Background

The causal genetic relationship between common parenteral manifestations of inflammatory bowel disease (IBD) and urolithiasis remains unclear because their timing is difficult to determine. This study investigated the causal genetic association between IBD and urolithiasis using Mendelian randomization (MR) based on data from large population-based genome-wide association studies (GWASs).

Methods

A two-sample MR analysis was... Читать дальше...



Unmet need for alcohol use disorder treatment in reproductive-age females, with emphasis on pregnant and parenting populations in the United States: Findings from NSDUH 2015–2021

Plos.org 

by Anna Shchetinina, Natalie Slopen

The negative effects of alcohol use can transmit intergenerational harm if alcohol use disorder (AUD) occurs during pregnancy and/or while parenting a child. Prenatal alcohol exposure is the leading preventable cause of congenital anomalies in the USA, and heavy drinking in women has been on the rise, further accelerated by the COVID-19 pandemic. This study describes the most recent patterns in the past year AUD prevalence and treatment among reproductive-aged women... Читать дальше...

Who shares fake news on social media? Evidence from vaccines and infertility claims in sub-Saharan Africa

Plos.org 

by Kerstin Unfried, Jan Priebe

The widespread dissemination of misinformation on social media is a serious threat to global health. To a large extent, it is still unclear who actually shares health-related misinformation deliberately and accidentally. We conducted a large-scale online survey among 5,307 Facebook users in six sub-Saharan African countries, in which we collected information on sharing of fake news and truth discernment. We estimate the magnitude and determinants of deliberate... Читать дальше...

Determinants of the happiness of adolescents: A leisure perspective

Plos.org 

by Eui-Jae Kim, Hyun-Wook Kang, Seong-Man Park

Leisure plays a key role in the happiness of youth. Studies have shown that various factors of leisure, such as the type, the time, the cost, and the space, have an influence on the adolescents’ happiness. However, little is known about which of these factors is a major factor in youth’s happiness. The purpose of this study is to explore the leisure factors that determine happiness in adolescents by examining the relationship between happiness and various leisure factors. Читать дальше...

A fast comparative genome browser for diverse bacteria and archaea

Plos.org 

by Morgan N. Price, Adam P. Arkin

Genome sequencing has revealed an incredible diversity of bacteria and archaea, but there are no fast and convenient tools for browsing across these genomes. It is cumbersome to view the prevalence of homologs for a protein of interest, or the gene neighborhoods of those homologs, across the diversity of the prokaryotes. We developed a web-based tool, fast.genomics, that uses two strategies to support fast browsing across the diversity of prokaryotes. First, the database of genomes is split up. Читать дальше...

Diet modulates strongyle infection and microbiota in the large intestine of horses

Plos.org 

by Noémie Laroche, Pauline Grimm, Samy Julliand, Gabriele Sorci

The use of anthelminthic drugs has several drawbacks, including the selection of resistant parasite strains. Alternative avenues to mitigate the negative effects of helminth infection involve dietary interventions that might affect resistance and/or tolerance by improving host immunity, modulating the microbiota, or exerting direct anthelmintic effects. The aim of this study was to assess the impact of diet on strongyle infection in horses... Читать дальше...

Symbiotic revolutions at the interface of genomics and microbiology

Plos.org 

by John M. Archibald

Symbiosis is an old idea with a contentious history. New genomic technologies and research paradigms are fueling a shift in some of its central tenets; we need to be humble and open-minded about what the data are telling us. Symbiosis is an old idea with a contentious history. New genomic technologies and research paradigms are fueling a shift in some of its central tenets; this Perspective argues that we need to be humble and open-minded about what the data are telling us.

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