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2024

Новости за 11.04.2024

Research on the chemical oxygen demand spectral inversion model in water based on IPLS-GAN-SVM hybrid algorithm

Plos.org 

by Qirong Lu, Jian Zou, Yingya Ye, Zexin Wang

Spectral collinearity and limited spectral datasets are the problems influencing Chemical Oxygen Demand (COD) modeling. To address the first problem and obtain optimal modeling range, the spectra are preprocessed using six methods including Standard Normal Variate, Savitzky-Golay Smoothing Filtering (SG) etc. Subsequently, the 190–350 nm spectral range is divided into 10 subintervals, and Interval Partial Least Squares (IPLS) is used to perform PLS modeling on each interval. Читать дальше...

Robustness of radiomic features in 123I-ioflupane-dopamine transporter single-photon emission computer tomography scan

Plos.org 

by Viktor Laskov, David Rothbauer, Hana Malikova

Radiomic features are usually used to predict target variables such as the absence or presence of a disease, treatment response, or time to symptom progression. One of the potential clinical applications is in patients with Parkinson’s disease. Robust radiomic features for this specific imaging method have not yet been identified, which is necessary for proper feature selection. Thus, we are assessing the robustness of radiomic features in dopamine transporter imaging (DaT). Читать дальше...



Specific nanoprobe design for MRI: Targeting laminin in the blood-brain barrier to follow alteration due to neuroinflammation

Plos.org 

by Juan F. Zapata-Acevedo, Mónica Losada-Barragán, Johann F. Osma, Juan C. Cruz, Andreas Reiber, Klaus G. Petry, Amael Caillard, Audrey Sauldubois, Daniel Llamosa Pérez, Aníbal José Morillo Zárate, Sonia Bermúdez Muñoz, Agustín Daza Moreno, Rafaela V. Silva, Carmen Infante-Duarte, William Chamorro-Coral, Rodrigo E. González-Reyes, Karina Vargas-Sánchez

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Towards secure and efficient integration of blockchain and 6G networks

Plos.org 

by Yang Liu, Song Peng, Miaomiao Zhang, Shidong Shi, Jianhao Fu

The future of communication systems is undergoing a transformative shift towards intelligence, efficiency, and flexibility. Presently, the amalgamation of blockchain technology and the sixth-generation mobile communication network (6G) has garnered significant attention, as their fusion is poised to profoundly impact the digital economy and society at large. However, the convergence of blockchain and 6G networks poses challenges pertaining to security and performance. Читать дальше...

Effects of summer schools: Who benefits the most?

Plos.org 

by Mélanie Monfrance, Carla Haelermans, Trudie Schils

This study investigates whether publicly funded summer school programs in secondary education are of substantive meaning for the math performance of students from lower socioeconomic backgrounds. More specifically, we explore whether this is the case when the summer programs are not explicitly aimed at low-SES students. In this context, we investigate whether summer schools in the Netherlands can decrease inequalities of opportunities in education. Читать дальше...

Predictive value of CD86 for the occurrence of sepsis (Sepsis-3) in patients with infection

Plos.org 

by Dan lv, Keji Zhang, Changqing Zhu, Xinhui Xu, Hao Gong, Li Liu

This prospective observational study explored the predictive value of CD86 in the early diagnosis of sepsis in the emergency department. The primary endpoint was the factors associated with a diagnosis of sepsis. The secondary endpoint was the factors associated with mortality among patients with sepsis. It enrolled inpatients with infection or high clinical suspicion of infection in the emergency department of a tertiary Hospital between September 2019 and June 2021. Читать дальше...

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Travel-эксперт Тариел Гажиенко: топ 5 мест для путешествий в летний сезон


The quantitative genetics of gene expression in Mimulus guttatus

Plos.org 

by Paris Veltsos, John K. Kelly

Gene expression can be influenced by genetic variants that are closely linked to the expressed gene (cis eQTLs) and variants in other parts of the genome (trans eQTLs). We created a multiparental mapping population by sampling genotypes from a single natural population of Mimulus guttatus and scored gene expression in the leaves of 1,588 plants. We find that nearly every measured gene exhibits cis regulatory variation (91% have FDR < 0.05). cis eQTLs are... Читать дальше...

Ten simple rules for leading a successful undergraduate-intensive research lab

Plos.org 

by KJE Hickman, Geoffrey Zahn

Participating in mentored research is an enormous benefit to undergraduate students. These immersive experiences can dramatically improve retention and completion rates, especially for students from traditionally underserved populations in STEM disciplines. Scientists typically do not receive any formal training in management or group dynamics before taking on the role of a lab head. Thus, peer forums and shared wisdom are crucial for developing the vision and... Читать дальше...

Interpreting population- and family-based genome-wide association studies in the presence of confounding

Plos.org 

by Carl Veller, Graham M. Coop

A central aim of genome-wide association studies (GWASs) is to estimate direct genetic effects: the causal effects on an individual’s phenotype of the alleles that they carry. However, estimates of direct effects can be subject to genetic and environmental confounding and can also absorb the “indirect” genetic effects of relatives’ genotypes. Recently, an important development in controlling for these confounds has been the use of within-family GWASs, which... Читать дальше...


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