Новости за 23.07.2024

Polycystic ovary syndrome, or PCOS, is a common endocrine disorder characterized by elevated levels of male sex hormones, known as androgens, in females. In addition to irregular menstrual cycles, enlarged or cyst-filled ovaries, increased body hair, and acne, patients with PCOS might have problems with fertility and metabolic issues, such as insulin resistance. Current treatment options like birth control pills and metformin tend to target only specific symptoms of the condition.

Roughly one-third of patients experienced symptoms such as headaches, nausea, insomnia, and irritability after discontinuing their use of antidepressants, according to an analysis of 79 studies involving more than 21 000 participants. The symptoms were attributable to patient expectations about the adverse effects of stopping the drug in about 17% of participants. After accounting for this, roughly 1 in 7 people had antidepressant discontinuation symptoms, the researchers reported in The Lancet Psychiatry. Читать дальше...

Only about one-third of participants in trials evaluating medical devices were women, a new systematic review of 195 trials, the majority of which were conducted between 2013 and 2022, found. The researchers found no increase in the percentage of women included as participants over time, continuing a decades-long trend of women being underrepresented in clinical trials for devices.

About one-third of people with preexisting heart disease who were exposed to very high temperatures experienced asymptomatic heat–induced cardiac ischemia, or poor oxygen delivery to the heart, a recent study published in Annals of Internal Medicine found. The findings were based on data from 61 participants: 41 healthy young and older adults as well as 20 older people with coronary artery disease (CAD).

The US National Institutes of Health (NIH) recently announced that it would invest $30 million over the next 2 years to test the feasibility of a primary care research network, called the Communities Advancing Research Equity for Health. The network’s aim is to integrate clinical research into community–based primary care, particularly in underserved areas. This would mean expanding opportunities for people to participate in clinical trials and other research and using that evidence to inform better patient care and outcomes.

In the largest study of its kind, GSK’s two-drug regimen Dovato demonstrated non-inferior efficacy compared to Gilead Sciences’ three-drug regimen Biktarvy for the treatment of HIV-1.

Date: 07/23/2024
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