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Новости за 22.08.2024



A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in C. elegans

Plos.org 

by Shaonil Binti, Adison G. Linder, Philip T. Edeen, David S. Fay

Protein tyrosine phosphatases non-receptor type (PTPNs) have been studied extensively in the context of the adaptive immune system; however, their roles beyond immunoregulation are less well explored. Here we identify novel functions for the conserved C. elegans phosphatase PTPN-22, establishing its role in nematode molting, cell adhesion, and cytoskeletal regulation. Through a non-biased genetic screen, we found that loss... Читать дальше...

An empirical appraisal of eLife’s assessment vocabulary

Plos.org 

by Tom E. Hardwicke, Sarah R. Schiavone, Beth Clarke, Simine Vazire

Research articles published by the journal eLife are accompanied by short evaluation statements that use phrases from a prescribed vocabulary to evaluate research on 2 dimensions: importance and strength of support. Intuitively, the prescribed phrases appear to be highly synonymous (e.g., important/valuable, compelling/convincing) and the vocabulary’s ordinal structure may not be obvious to readers. We conducted an online... Читать дальше...

The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord

Plos.org 

by Zonglai Liang, Daniel Christiaan Dondorp, Marios Chatzigeorgiou

During embryonic development, tissues and organs are gradually shaped into their functional morphologies through a series of spatiotemporally tightly orchestrated cell behaviors. A highly conserved organ shape across metazoans is the epithelial tube. Tube morphogenesis is a complex multistep process of carefully choreographed cell behaviors such as convergent extension, cell elongation, and lumen formation. The identity of... Читать дальше...

Elephant Rumblings: Pruitt, Logjams, Canesco, plus a Wilson update

Athletics Nation 

Cary Edmondson-USA TODAY Sports

MLB news roundup

Good morning A’s fans! Time to rise and shine.

The A’s fell to the Tampa Bay Rays in last night’s contest, though since it’s a four-game series the club still has a chance at splitting the series. It wasn’t all bad in the close 4-2 loss as Rule 5 rookie Mitch Spence set a career-high in strikeouts, JJ Bleday hit his 17th home run, and we also got a successful MLB debut from the last remaining piece of the Chris Bassitt trade. Читать дальше...

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Москва

Отделение СФР по Москве и Московской области предостерегает: не поддавайтесь на уловки мошенников!



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US Open

Медведев показал, как его семью встретили в Нью-Йорке перед US Open. Видео






Стены Международного аэропорта Владивосток украсили стихи приморских поэтов

«Амкал» остался единственным представителем Медиалиги в Кубке России

Тело женщины с травмами обнаружено в квартире на юго-западе Москвы

Китайская делегация посетила музей-заповедник «Горки Ленинские» в Подмосковье