Ovarian Aging and Fertility
This JAMA Insights discusses ovarian aging and provides strategies to address infertility due to ovarian aging.
This JAMA Insights discusses ovarian aging and provides strategies to address infertility due to ovarian aging.
In Reply We appreciate the letter from Dr Hu regarding additional points of consideration for our study on CKD. We agree that it is critical to consider pregnancy in studies assessing sex disparities in health care. For our study, females of reproductive age accounted for only 0.8% of our cohort (n = 35). We did not expect this small number of patients to change our results, so we did not plan a subgroup analysis. However, the care of patients before, during, and after pregnancy highlights opportunities for future research. Читать дальше...
To the Editor Although the study by Dr Rodriguez and colleagues provides a solid foundation for understanding gender differences in chronic kidney disease (CKD) management, several issues merit further discussion to enhance the study’s contributions to this critical area of health care.
The long list of empathy killers in medical practice is familiar: time constraints, financial imperatives, cross-cultural misunderstanding, interposed electronic health records, distancing telemedicine. Most alarmingly, now AI-based chatbots with their manufactured empathy threaten to supersede genuine human care. As these barriers between clinicians and patients grow, poetry can be critical in preserving the heartfelt empathy that joins us in healing. Many descriptive studies and some quantitative research support this assertion. Читать дальше...
Some might say I have a cervical myelopathy Thanks to my mother's arthritis. In fact, what I have is Connie's bum neck. (She lurched in and out of clinic for weeks Before any of us realized she was actually, Finally, inconceivably, stone-cold sober.) I have Juan's motheaten knee. (He came in with the world's phoniest limp. I was already giving him enough Percocet To kill a horse. No more, I said.) It was quickly replaced, that knee. I think he mostly forgave me. I have Debra's dead hip And her gimpy hands And her battered, useless shoulder. Читать дальше...
In Reply We thank Dr Xiang and colleagues for their Letter, in which they express concern that transfusion of platelets, prolonged aortic cross-clamp time, sedation protocols in the ICU, delirium assessment methods, and different EEG monitoring devices might have confounded the results of the ENGAGES-Canada trial.
To the Editor A recent trial concluded that among older adults undergoing cardiac surgery, electroencephalography (EEG)-guided anesthetic administration to minimize EEG suppression, compared with usual care, did not decrease the incidence of postoperative delirium. We have several concerns about this trial.
This study identifies state policies authorizing law enforcement access to prescription drug monitoring program data and discusses the characteristics of those policies, particularly in states with laws banning gender-affirming care.
In this narrative medicine essay, a pediatrician thwarted a likely fatal cancer after undergoing genetic testing after noticing a pattern in her family that turned out to be caused by a genetic variation.
In Reply I appreciate the comments of Mr Rothstein and Dr Siegal on my recent Viewpoint about the Declaration of Helsinki. We agree on many points, including that the duty owed by physicians to patients can be “inconsistent with clinical research whose purpose is to produce generalizable knowledge.” I certainly concur that “the important ends of medical research do not justify any and all means.” Indeed, appropriately protecting research participants has long been at the core of research ethics. And as Rothstein and Siegal also note... Читать дальше...
To the Editor Although the title of the recent Viewpoint article “Protecting Participants Is Not the Top Priority in Clinical Research” is correct, we disagree with this Viewpoint because it failed to recognize that at least since the Nuremberg Code, protecting participants is the top priority of research ethics.
If there is any procedure that represents the apotheosis of the application of preventive medicine, it is the periodic physical examination. This is the most efficient method that modern medicine has for determining the ability of the individual human being to continue his life in such a manner that he may reach the age to which the tables of life expectancy indicate he is entitled. It is not surprising, then, that the idea has received the spontaneous and wholehearted approval of all the nonmedical agencies to which it may have been broached. Читать дальше...
In the Viewpoint titled “The Science of Biosimilars—Updating Interchangeability,” published in the October 15, 2024, issue of JAMA, incorrect wording appeared in the first and third paragraphs. In the first sentence of the first paragraph, “Biosimilars Price and Competition” should have read “Biologics Price and Competition.” In the first sentence of the third paragraph, “we recently issued an update to our draft interchangeability guidance” should have read “we recently issued a draft guidance to... Читать дальше...
This Medical News article discusses the impact of the Texas abortion ban on obstetrician-gynecologists and their patients in the state and beyond.
A recent study found that time-restricted eating, in which daily dietary intake is limited to 8 to 10 consistent hours without mandating calorie reduction, may provide benefits for people with metabolic syndrome—a cluster of conditions that increase the risk of type 2 diabetes, stroke, and heart disease.
Commonly used, nonstandard arm positions can result in higher blood pressure readings, according to a trial published in JAMA Internal Medicine.
Older people with Alzheimer disease or its precursor, mild cognitive impairment, face an increased risk of falling, but researchers have now found that a fall could serve as a “sentinel event” that marks future risk for dementia.
People require almost 10 times as much iron after they become pregnant to support fetal development, but, for many, this need isn’t being met. Most women may be iron deficient by the third trimester, suggests a recent longitudinal study in The American Journal of Clinical Nutrition.
More people in their 40s with an average risk of colorectal cancer are being screened after the US Preventive Services Task Force lowered the recommended screening age from 50 to 45 years in 2021. A study published in JAMA Network Open found an uptick in screenings after the recommendation compared with the 20 months prior.
The first outbreak of Marburg virus disease (MVD) in the Republic of Rwanda has been confirmed, according to a US Centers for Disease Control and Prevention (CDC) health advisory. MVD is a rare but highly fatal viral hemorrhagic fever caused by infection with 1 of 2 zoonotic viruses, Marburg or Ravn, which are within the same virus family as Ebola viruses.
Despite the decline in death rates from breast cancer among women, the incidence of the disease has continued to rise in the US, by 1% a year from 2012 to 2021, according to an American Cancer Society analysis of data from the National Cancer Institute and the Centers for Disease Control and Prevention.
Thirteen people working on California dairy farms have been infected with avian influenza A(H5N1) virus, or H5N1 bird flu, the Centers for Disease Control and Prevention (CDC) announced in mid-October. No person-to-person spread has been detected in the ongoing outbreak, which has affected more than 300 dairy cattle herds in 14 states.
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