by The PLOS ONE Editors
by Paskari Odoi, Stella Neema, Birgitte J. Vennervald, Edridah M. Tukahebwa, Shona Wilson
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by Wendemagegn Enbiale
BackgroundNoma is a rapidly progressing, invasive, and debilitating orofacial disease that primarily affects the most vulnerable and marginalised populations worldwide. The highest- risk group includes pre-school children, exposed to other risk factors, such as malnutrition and poverty-related diseases. Since 2010, Ethiopia has reported an increasing number of noma cases, primarily identified through medical missions. Data on the disease burden and epidemiology are... Читать дальше...
by Mehrab E Hossain, Caitlin Keighley, Andrew H. Buultjens, Jessica L. Porter, Paul D. R. Johnson, Timothy P. Stinear, Maria Globan, Caroline J. Lavender, Jake A. Lacey, Norelle L. Sherry, Anton Forsyth, Mark Formby, Ian Marr
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by Mable Mutengo, Michaela Kaduková, Namwiinga R. Mulunda, Freeman Chabala, Alejandro Dashti, Kyoko Hayashida, Stanley Chinyanta, Kelly Chisanga, Lourdes Castro, Sergio Sánchez, James Mwansa, Pamela C. Köster, David González-Barrio, Jenny G. Maloney, Mónica Santín, Javier Sotillo, David Carmena
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by Bereket Abebayehu Tegene, Thomas Asfaw Atnafu
BackgroundLeprosy is one of the neglected tropical diseases associated with significant morbidity in endemic regions. It causes disability affecting the daily activities and social participation of affected individuals. Understanding the prevalence and trend of leprosy-related disability throughout the world and the accuracy of disability data counted by WHO is crucial in guiding efforts to be made towards the targets set by WHO to be achieved by 2030. Читать дальше...
by Pedro Pablo Martínez-Vega, Marian Rivera-Pérez, Gabrielle Pellegrin, Antoine Amblard-Rambert, Jorge Andrés Calderón-Quintal, Christian Barnabé, Christian Teh-Poot, Hugo Ruiz-Piña, Antonio Ortega-Pacheco, Etienne Waleckx
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by Eric Nyarko, Edmund Fosu Agyemang, Ebenezer Kwesi Ameho, Louis Agyekum, José María Gutiérrez, Eduardo Alberto Fernandez
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by Thaís Alkifeles Costa, Matheus Soares Arruda, Gabriela Fernanda Garcia Oliveira, Erik Vinicius de Sousa Reis, Anna Catarina Dias Soares Guimarães, Gabriel Dias Moreira, Nidia Esther Colquehuanca Arias, Marina do Vale Beirão, Nikos Vasilakis, Kathryn A. Hanley, Betânia Paiva Drumond
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by Alexander Rakowski, Remo Monti, Christoph Lippert
Genome-wide association studies (GWAS) traditionally analyze single traits, e.g., disease diagnoses or biomarkers. Nowadays, large-scale cohorts such as UK Biobank (UKB) collect imaging data with sample sizes large enough to perform genetic association testing. Typical approaches to GWAS on high-dimensional modalities extract predefined features from the data, e.g., volumes of regions of interest. This limits the scope of such studies to... Читать дальше...
by Jonathan Amezquita, Muriel Desbois, Karla J. Opperman, Joseph S. Pak, Elyse L. Christensen, Nikki T. Nguyen, Karen Diaz-Garcia, Melissa A. Borgen, Brock Grill
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by Tiegh Taylor, Hongyu Vicky Zhu, Sakthi D. Moorthy, Nawrah Khader, Jennifer A. Mitchell
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by Jorin Overwiening, Federico Tesler, Domenico Guarino, Alain Destexhe
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by Victor Geadah, Stefan Horoi, Giancarlo Kerg, Guy Wolf, Guillaume Lajoie
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by Emine Celiker, Charlie Woodrow, Òscar Guadayol, Leonidas-Romanos Davranoglou, Christian M. Schlepütz, Beth Mortimer, Graham K. Taylor, Stuart Humphries, Fernando Montealegre-Z
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by Ahmed Akib Jawad Karim, Muhammad Zawad Mahmud, Riasat Khan
Mosquito-related diseases pose a significant threat to global public health, necessitating efficient and accurate mosquito classification for effective surveillance and control. This work presents an innovative approach to mosquito classification by leveraging state-of-the-art vision transformers and open-set learning techniques. A novel framework has been introduced that integrates Transformer-based deep learning models with comprehensive... Читать дальше...
by Asier Ortega-Legarreta, Sara Palomino-Echeverria, Estefania Huergo, Vincenzo Lagani, Narsis A. Kiani, Pierre-Emmanuel Rautou, Nuria Planell Picola, Jesper Tegner, David Gomez-Cabrero
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by Pengyu Liu, Jacob Lusk, Nataša Jonoska, Mariel Vázquez
R-loops are a class of non-canonical nucleic acid structures that typically form during transcription when the nascent RNA hybridizes the DNA template strand, leaving the non-template DNA strand unpaired. These structures are abundant in nature and play important physiological and pathological roles. Recent research shows that DNA sequence and topology affect R-loops, yet it remains unclear how these and other factors contribute to R-loop formation. Читать дальше...
by Karim G. Habashy, Benjamin D. Evans, Dan F. M. Goodman, Jeffrey S. Bowers
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by Tina Lenče, Johannes Sulzer, Kilian Andress, Anne-Sophie Gribling-Burrer, Vanessa Lamm-Schmidt, Lars Barquist, Redmond P. Smyth, Franziska Faber
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