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2024

Новости за 17.12.2024

‘The Masked Singer’ spoilers: The clues for Buffalos and Wasp

GoldDerby.com 

At long last, the remaining contestants from The Masked Singer Season 12 — Buffalos and Wasp — will compete for the Golden Mask during the Dec. 18 finale on Fox. But will the ultimate winner be Group A’s mammalian singing trio or Group B’s buzzed-about soloist? And, more importantly, which famous faces are hiding underneath the […]

JO Residence / Jacobsen Arquitetura

Archdaily.com 

Situated in a residential condominium in Guarujá, a city about an hour and a half from São Paulo, this summer retreat takes advantage of the main view to create solutions that prioritize privacy and enjoyment of the living and leisure spaces. This beach house was commissioned by a long-standing client of the office, a couple who spends their vacations on the coast with their family and friends. During our first visit to the site, we understood that we should explore the back of the plot, which... Читать дальше...



Zinc homeostasis regulates caspase activity and inflammasome activation

Plos.org 

by Xiao Gong, Weidi Gu, Shuo Fu, Gonglu Zou, Zhengfan Jiang

Inflammasome activation drives pyroptotic cell death and the release of inflammatory cytokines, and many diseases involve its overactivation. Zinc is essential for all organisms as a trace element, but its functions in innate immunity remain undefined. Here, we reported that Zn2+ inhibits caspase-1 to hinder inflammasome activation. We first identified the zinc exporter solute carrier family 30 member 1 (SLC30A1) as an inflammasome regulator... Читать дальше...

IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia

Plos.org 

by Stefan Nagel, Corinna Meyer, Claudia Pommerenke

Homeobox genes encode transcription factors which organize differentiation processes in all tissue types including the hematopoietic compartment. Recently, we have reported physiological expression of TALE-class homeobox gene IRX1 in early myelopoiesis restricted to the megakaryocyte-erythroid-progenitor stage and in early B-cell development to the pro-B-cell stage. In contrast, sister homeobox genes IRX2, IRX3 and IRX5 are aberrantly activated... Читать дальше...

Новости России
Москва

Ткани премиум-класса – обзор ассортимента «Тканель»


Gradient boosting for yield prediction of elite maize hybrid ZhengDan 958

Plos.org 

by Oumnia Ennaji, Sfia Baha, Leonardus Vergutz, Achraf El Allali

Understanding accurate methods for predicting yields in complex agricultural systems is critical for effective nutrient management and crop growth. Machine learning has proven to be an important tool in this context. Numerous studies have investigated its potential for predicting yields under different conditions. Among these algorithms, Random Forest (RF) has gained prominence due to its ability to manage large data sets with high dimensions... Читать дальше...

An experimental study of simulated grant peer review: Gender differences and psychometric characteristics of proposal scores

Plos.org 

by Karen B. Schmaling, Stephen A. Gallo

Peer review is a decisive factor in selecting research grant proposals for funding. The usefulness of peer review depends in part on the agreement of multiple reviewers’ judgments of the same proposal, and on each reviewer’s consistency in judging proposals. Peer reviewers are also instructed to disregard characteristics that are not among the evaluation criteria. However, for example, the gender identity—of the investigator or reviewer—may be associated with differing evaluations. Читать дальше...

The internet of things deployed for occupational health and safety purposes: A qualitative study of opportunities and ethical issues

Plos.org 

by Maeva El Bouchikhi, Sophie Weerts, Christine Clavien

The deployment of the Internet of Things (IoT) technology (connected devices enabling algorithmic analysis of behaviour and individualized feedback) has been growing increasingly over the last decades, including in the workplace where they can serve occupational safety and health (OSH) purposes. However, although the IoT is deployed for good aims, the use of these devices raises numerous ethical issues which have had little literature specifically dedicated to them. Читать дальше...

Individual, household, and community-level determinants of undernutrition among pregnant women in the northern zone of the Sidama region, Ethiopia: A multi-level modified Poisson regression analysis

Plos.org 

by Amanuel Yoseph, Lakew Mussie, Mehretu Belayneh

Introduction

In Ethiopia, maternal undernutrition is a major public health concern. However, comprehensive evidence is lacking in the southern part of Ethiopia, specifically the household and community-level related determinants of undernutrition. Besides, the evidence about the prevalence and determinants of undernutrition is not yet documented in the current study setting. Thus, this study aimed to determine the prevalence of undernutrition... Читать дальше...


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Новости тенниса
ATP

Российский теннисист Андрей Рублев проиграл 102-й ракетке мира и не прошел в финал турнира ATP в Монпелье






Эксперт предупредила о штрафах за долгий прогрев автомобиля в жилой зоне

Отец Яниса Тиммы рассказал, что Седокова называла его сына “колхозником”

В России увеличился спрос на виниловые пластинки

Взрывы и черный дым: в Москве пылает ангар с газовыми баллонами