Platelet to lymphocyte ratio as a predictive factor of 30-day mortality in patients with acute mesenteric ischemia

by Emmanuel Augène, Fabien Lareyre, Julien Chikande, Lucas Guidi, Ali Ballaith, Jean-Nicolas Bossert, Yann Pelletier, Caroline Caradu, Réda Hassen-Khodja, Juliette Raffort

Acute mesenteric ischemia is associated with high rates of mortality. The aim of this study was to investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) on 30-day outcomes in patients with acute mesenteric ischemia.

Consecutive patients who were admitted for an acute mesenteric ischemia were retrospectively included. The full white blood count at the time of admission to the hospital was recorded. The population was divided into 4 subgroups according to the quartiles of the NLR and the PLR. The 30-day outcomes including the mortality and the complications were compared among the subgroups.

In total, 106 patients were included. A surgical treatment including revascularization and/or digestive resection was performed for 56 patients (52.8%). The 30-day all-cause mortality was 72 patients (67.9%). Patients with higher PLR value (PLR >429.3) had significantly higher rate of mortality compared to the other groups (80.8% vs 46.2%, 66.7% and 77.8%, p = 0.03). No significant difference on 30-day outcome was observed among the subgroups divided according to the NLR.

The PLR, but not the NLR, is a predictive factor of 30-day mortality in patients with acute mesenteric ischemia.