A recent study has established that high dose intake of opioid is not effective in reducing pain.The researchers' team from Central Arkansas and Minneapolis VA Health Care Systems and three universities have suggested after studying available data that patients who got their opioid dosage increased were not helped by the higher dosage as compared to those, who continued with earlier dosage.The Veterans Affairs study looked at prescribing data of more than 50,000 VA patients taking opioids. The findings led the study authors to warn: "Clinicians should exercise extreme caution when embarking on a path of increasing opioid doses to manage non-cancer pain."The results were published in the January 9 issue of the journal 'Pain'.A companion study by the same team that appeared online on January 15, in addition, confirmed the increased risk of side effects from higher doses.Lead author Dr Corey Hayes in a University of Arkansas for Medical Sciences report said: "You don't see the benefit, ..
