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Март
2022

Discovery of an immune escape mechanism promoting Listeria infection of the central nervous system

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Some 'hypervirulent' strains of Listeria monocytogenes have a greater capacity to infect the central nervous system. Scientists have discovered a mechanism that enables cells infected with Listeria monocytogenes to escape immune responses. This mechanism provides infected cells circulating in the blood with a higher probability of adhering to and infecting cells of cerebral vessels, thereby enabling bacteria to cross the blood-brain barrier and infect the brain.



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