NFL Week 4: Sports betting picks against the spread for every game this week

Joe Burrow and the Cincinnati Bengals are off to a shaky start to the season, looking quite different from the team that marched to a Super Bowl appearance last year.

Still, this team has a lot of offensive firepower, and facing a Miami team that is coming off of an exhausting game against the Buffalo Bills on a short week, Burrow should be able to put enough points on the board to cover the number.

Kirk Cousins stunk in primetime two weeks ago, something that has become a theme in his professional career. But if Cousins plays bad in primetime and okay/pretty good during the afternoon window of games, logic would dictate that he will be unstoppable in a game that kicks off from London around 9:30am EST.

Jokes aside, the Saints are struggling with injuries, and the Vikings are due to wake up after a couple of down weeks.

The Jacksonville Jaguars look like a legitimate contender through three weeks of football. The Philadelphia Eagles look like they may be the most complete team in the NFL.

Rock, meet hard place. This game should be a good one, but if I have to pick a side, this feels like a lot of points to be giving a Jaguars offense that has plenty of different looks it can throw.

The Los Angeles Chargers have once again been bitten by the injury bug, with stars Joey Bosa and Rashawn Slater both out for the foreseeable future.

Given we still don't know if quarterback Justin Herbert is back at 100%, it feels impossible to lay points on the road with this Chargers team. Too many question marks.

The Steelers are playing at home — against a lesser opponent, with a few extra days of rest, and coming off of a second-straight loss. With another loss potentially putting them DOA in the race for the AFC North, this feels like a game that Mike Tomlin finds a way to win.

I hate to bet against the Bills coming off of a loss, but spotting Lamar Jackson a field goal at home feels like a dangerous proposition. Jackson is a one-man wrecking crew, and he hasn't been stopped yet this season.

The Detroit Lions have scored more points than any team in the NFL aside from the Baltimore Ravens. The Seattle Seahawks have scored fewer points than any team in the NFL aside from the Cowboys, Broncos, and Colts.

Don't overthink it.

After two weeks of unsuccessfully betting against Cooper Rush, it is time to cut my losses. Rush has proven himself entirely capable of keeping the Cowboys offense moving, and with the way the Dallas defensive front has been playing the past few weeks, Commanders quarterback Carson Wentz could be in for another long day.

The Falcons have once again unlocked Cordarrelle Patterson, who is currently third among all rushers in the NFL. While the Browns dual-threat running attack of Nick Chubb and Kareem Hunt is possibly the best in the league, the Falcons should have enough scoring of their own to keep pace.

This is going to be an ugly game. It is difficult to imagine more than 30 points being scored. With expectations low for both offenses, it feels like getting a field goal on the underdog is a solid value.

Coming off an impressive win against the Chiefs, it feels like a great time to fade the Indianapolis Colts. Just as their fortunes swung dramatically from losing 24-0 to the Jaguars to beating one of the best teams in football, those fortunes can swing right back again against a divisional rival that needs to right the ship after a rocky start.

The Cardinals are running out of time to figure it out. With a daunting schedule during the second half of the season, this is not a game Arizona can afford to drop if they hope to contend for a playoff spot.

The Las Vegas Raiders should be better than 0-3. They definitely shouldn't have the worst record in football. And yet, here we are.

I have to believe Derek Carr gets this offense going eventually. After hooking up with newly arrived stud receiver Davante Adams for 10 receptions and 141 yards in Week 1, Carr has found Adams just seven times since. That dynamic feels ready to flip at any moment.

If I have to bet on Aaron Rodgers or Brian Hoyer, I will bet Rodgers every time, regardless of what the spread is.

Patrick Mahomes knows how to put on a show in primetime. Meanwhile, Tom Brady and the Buccaneers offense still look lost, having failed to score more than 20 points in a game this season.

Until Brady and company shake off the rust and start looking like a real team, I'm taking Mahomes.

Jimmy Garoppolo is 9-1 coming off a loss as the starting quarterback for the San Francisco 49ers. The 49ers have beaten the Rams in six of their past seven meetings.

Even if the 49ers performance last week was dreadful, those are two trends worth backing.