UPDATES: Ohio State 21, Michigan State 13

EAST LANSING, Mich. (WCMH) -- Third-ranked and unbeaten Ohio State (5-0) hits the road for the first time this season to take on a struggling Michigan State (2-3) squad.

The Spartans have dropped three straight games and are just 3-15 against the Buckeyes since 2000 and haven't beaten Ohio State in East Lansing since 1999.

Second Quarter

Henderson picked up the first down on a carry behind left tackle Paris Johnson Jr, setting up a 51-yard touchdown throw from Stroud to Julian Fleming on a post route and putting the Buckeyes up by two touchdowns just 30 seconds into the quarter.

Brown was whistled for another pass interference to keep Michigan State's next drive alive at the OSU 46 yard line, and later another on a horse collar tackle on Jarek Broussard. Brown is having a tough game so far, with three penalties and a deep ball allowed.

Brown was whistled for another pass interference on the drive, and Zach Harrison nullified a third down sack by Michael Hall Jr when he committed a hands to the face penalty. That led to an 18 yard touchdown grab by Jayden Reed off a pretty back shoulder throw from Thorne. The extra point was missed, so OSU's lead sits at 21-13 with 10:43 remaining in the half.

Brown is having a tough game for OSU, with a pair of pass interference calls, a horse collar tackle and a big play catch allowed.

First Quarter

Ohio State kicked off out of bounds, giving Michigan State the ball at its own 35-yard-line.

The Spartans hit a 20-yard gain on a pretty throw and catch by Payton Thorne to Jayden Reed to gain a first drive, but the drive was ended when Thorne threw into triple coverage and was picked off in the end zone by Lathan Ransom.

The Buckeyes took the ball at their own 20 and reeled off four big plays on a scoring drive that covered 80 yards --a 16 yard reverse to Emeka Egbuka, a 26-yard cutback run by TreVeyon Henderson, a 24 yard catch by Egbuka and the 19-yard touchdown strike from Stroud to Marvin Harrison Jr, who went up and over an MSU defender to make the grab. Ohio State used seven plays and consumed 2:20 of clock. The touchdown was the seventh of the season for Harrison Jr.

Michigan State went three and out on its second drive, with OSU taking the punt at its own 10 yard line after a 57-yard boot by Bryce Barringer.

Ohio State gained a first down before Stroud inexpicably threw the ball right to Spartans defender Charles Brantley, who turned it into a 32-yard Pick 6 and tied the game. It was an obvious miscommunication between Stroud and Egbuka, who thought the route was going farther upfield.

The Buckeyes countered with a 69-yard scoring strike from Stroud to Egbuka on a busted coverage by Michigan State. The Spartans corners were in man and Egbuka ran right past his guy for the touchdown. OSU covered 75 yards in three plays.

MSU had third and long on its next possession but was bailed out by a Cameron Brown pass interference penalty, and used OSU's pressure against it with a pass to Tre Mosley in the flat for 14 yards for another conversion. The Buckeyes buckled down and got aggressive, sacking Thorne on third-and-six to take the Spartans out of field goal range. Barringer punted down to the OSU three, where the Buckeyes will take over.

The Buckeyes moved the ball to its own 42 as the quarter ended, and is staring at a fourth-and-1.

Henderson had his best first quarter of the season, netting 77 yards on just 10 carries.

OSU will once again be without the services of Jaxon Smith-Njigba, who has played little since being injured in the opener against Notre Dame, as well as running back Miyan Williams, who tied a school record with five touchdowns against Rutgers last weekend.

The Buckeyes are expected to have TreVeyon Henderson back in the fold after he was a late scratch against the Scarlet Knights. OSU is looking to stay unbeaten before its bye week