Researchers solve the problem of functionalizing pyridine in the meta-position

In chemicals used in agriculture, as well as in pharmaceuticals and a variety of materials, pyridines are often found as so-called functional units that decisively determine the chemical properties of substances. Pyridines belong to the group of ring-shaped carbon-hydrogen (C-H) compounds ("heterocycles"), and they contain a nitrogen atom (N). For chemists, the direct functionalization of the carbon-hydrogen bonds (C-H bonds) of pyridines is a straightforward approach to designing and modifying complex molecules, including in the final stage of the synthesis sequence.