Enzyme-metal, single-atom hybrid catalysts for efficient one-pot chemoenzymatic reactions

The merging of different types of catalysis including enzymatic, homogeneous, and heterogeneous catalysis is fundamentally important for understanding both catalysis at the atomic level and the design of novel hybrid catalysts. The latter strives for the ideal catalyst that can drive complex tandem reactions efficiently in a one-pot manner and simplify the whole chemical production and separation process. Artificial enzymes that merge enzymatic, homogeneous, and heterogeneous catalysis provide a promising platform for developing novel hybrid catalysts that can achieve this goal efficiently under ambient conditions.