Junior Associate Professor Kazuo Takayama and his research team used human airway organoids to screen autophagy-related compounds and found cycloheximide and thapsigargin to show strong antiviral effects against SARS-CoV-2. Further testing revealed cycloheximide to be also effective against six SARS-CoV-2 mutant strains and other human coronaviruses. Results of this study were published online in Molecular Pharmaceutics on March 22, 2023.
