Sharon Osbourne swears off weight loss and cosmetic treatments after experiencing the downsides of Ozempic

• Sharon Osbourne has expressed regret over taking the weight-loss drug Ozempic.
• "I'm through with the weight loss and all that cosmetic stuff," she told The Guardian.
• Osbourne, 71, says she now weighs less than 100 pounds and "can't put on weight." 

Sharon Osbourne has expressed regret over taking the buzzy weight-loss drug Ozempic, stating that she now weighs less than 100 pounds and "can't put on weight." 

In an interview with The Guardian, Osbourne, 71, highlighted the downsides of Ozempic, a diabetes drug that also causes weight loss. She said that after dropping 42 pounds in four months, she's now "through with the weight loss and all that cosmetic stuff."

"I was injecting myself with Ozempic, and I lost three stone in four months," Osbourne said (in British weight measurement, a stone is equivalent to 14 pounds). "Too much. I now weigh seven stone and can't put on weight." 

There are 14 pounds in a stone, according to a British weight measurement.

She added that her husband, Ozzy Osbourne, "says I look like Nancy Reagan," whose small frame was the subject of scrutiny from the media during her husband's time in office.

Osbourne has previously talked about her experience taking the weight loss drug. In an interview with the Daily Mail last year, she warned those interested in taking Ozempic to "be careful what you wish for."

"You can lose so much weight and it's easy to become addicted to that, which is very dangerous," she said. "I couldn't stop losing weight and now I've lost 42 pounds and I can't afford to lose any more."

"I started on Ozempic last December and I've been off it for a while now, but my warning is don't give it to teenagers, it's just too easy," she continued.

Ozempic is the brand name for semaglutide, an FDA-approved drug used to treat diabetes. Also sold under the brand names Wegovy and Rybelsus, it has surged in popularity since it was approved by the FDA as a treatment for obesity in 2022. 

Dozens of A-listers have admitted to using semaglutide, including Elon Musk, Charles Barkley, and Amy Schumer, among others.

The drug works by suppressing appetite, but side effects such as muscle loss, nausea, and diarrhea have been reported. It's common to regain the weight after stopping treatment, according to one doctor Business Insider spoke to.

Osbourne also reflected on her previous cosmetic procedures, which include breast implants and Botox, in an interview with The Times in December.

At the time, she said that a facelift she got in 2021 left her looking like Cyclops and was the "worst thing" she's ever done.