New system triggers cellular waste disposal

Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.