Elucidating the mechanism underlying de novo membrane formation during gametogenesis

Researchers at University of Tsukuba have meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings reveal that during sporulation, the endoplasmic reticulum exit sites, which represent the starting points of the secretory pathway, are remodeled. This remodeling enables cells to efficiently transport proteins and membrane lipids, facilitating the formation of nascent spore membranes.