Not just a garbage truck: No-go decay plays a role during embryo development in zebrafish

by Alana R. Plastrik, Hani S. Zaher

In eukaryotes, defective mRNAs that impede the movement of the ribosome are subject to rapid decay via no-go decay (NGD). In this issue of PLOS Biology, Ishibashi and colleagues expand on the role of NGD and reveal new endogenous targets for the process in zebrafish.