The Guardian of the Brain – Microglia.
In mammalian brains, neurons are often considered the most abundant cells, but in reality, they are far outnumbered by another type of cell: glial cells. Glial cells account for about 90% of the total cellular content in the brain, with microglia making up about 20% of this glial population. Despite their smaller proportion, microglia play a crucial role in maintaining the tissue homeostasis of the central nervous system (CNS). Microglia are the primary immune cells of the CNS, and their functions extend beyond immune responses in diseases. They dynamically interact with neurons in the adult brain. In a healthy ...