A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ Hybridization-guided Single-Cell Raman-activated Sorting and Sequencing), utilizes a Raman-activated optical tweezers-based cell sorter developed by Qingdao Single-Cell Biotech Inc.